Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 8/20 | 0.63 |
| ▸ | TUBB | P07437 | 8/20 | 0.63 |
| ▸ | TUBA3C | P0DPH7 | 8/20 | 0.63 |
| ▸ | TUBA1B | P68363 | 8/20 | 0.63 |
| ▸ | TUBA4A | P68366 | 8/20 | 0.63 |
| ▸ | TUBB4B | P68371 | 8/20 | 0.63 |
| ▸ | TUBB3 | Q13509 | 8/20 | 0.63 |
| ▸ | TUBB2A | Q13885 | 8/20 | 0.63 |
| ▸ | TUBB8 | Q3ZCM7 | 8/20 | 0.63 |
| ▸ | TUBA3E | Q6PEY2 | 8/20 | 0.63 |
| ▸ | TUBA1A | Q71U36 | 8/20 | 0.63 |
| ▸ | TUBA1C | Q9BQE3 | 8/20 | 0.63 |
| ▸ | TUBB6 | Q9BUF5 | 8/20 | 0.63 |
| ▸ | TUBB2B | Q9BVA1 | 8/20 | 0.63 |
| ▸ | TUBB1 | Q9H4B7 | 8/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.63 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11120640 | 0.96 | TUBB4A (0.59) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL11552199 | 0.92 | TUBB4A (0.53) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL11212646 | 0.90 | TUBB4A (0.78) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL30785781 | 0.90 | TUBB4A (0.78) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL11549633 | 0.88 | NPC1 (0.56) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| Parbendazole SCHEMBL29409286 | 0.88 | TUBB4A (0.82) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| Parbendazole SCHEMBL259455 | 0.88 | TUBB4A (0.82) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL11120642 | 0.86 | TUBB4A (0.72) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL19191488 | 0.82 | TUBB4A (0.53) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL11540064 | 0.81 | NPC1 (0.47) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4173632-A | Fasciolicidal compositions | E. R. SQUIBB & SONS, INC. (US) | 1979-11-06 | — | — | US | claimed |
| EP-0279343-B1 | COMBINATIONS OF ANTHELMINTICALLY ACTIVE AGENTS | BAYER AG (DE) | 1991-06-05 | — | — | EP | disclosed |
| EP-0090368-A1 | Anthelmintic preparations | HOECHST UK LIMITED (GB) | 1983-10-05 | — | — | EP | disclosed |
| US-4173632-A | Fasciolicidal compositions | E. R. SQUIBB & SONS, INC. (US) | 1979-11-06 | — | — | US | disclosed |
| US-4173632-A | Fasciolicidal compositions | E. R. SQUIBB & SONS, INC. (US) | 1979-11-06 | — | — | US | disclosed |