⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15842 | 0.89 | — | — | |
| SCHEMBL14569692 | 0.89 | — | — | |
| SCHEMBL3322733 | 0.89 | — | — | |
| SCHEMBL31162289 | 0.89 | — | — | |
| SCHEMBL2368206 | 0.89 | KDM4E (0.33) | — | |
| SCHEMBL4193479 | 0.86 | — | — | |
| Methyl Alcohol SCHEMBL8598770 | 0.86 | — | — | |
| SCHEMBL18597177 | 0.85 | TFPI2 (0.38) | — | |
| SCHEMBL8687641 | 0.85 | ALDH1A1 (0.33) | — | |
| Water SCHEMBL11665768 | 0.85 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4988716-A | Inhibitors of slow reacting substance of anaphylaxis | SCHERING CORPORATION (US) | 1991-01-29 | — | — | US | disclosed |
| US-4889873-A | Inhibitors of slow reacting substance of anaphylaxis | SCHERING CORPORATION (US) | 1989-12-26 | — | — | US | disclosed |
| US-4798842-A | Inhibitors of slow reacting substance of anaphylaxis | SCHERING CORPORATION (US) | 1989-01-17 | — | — | US | disclosed |
| US-4758594-A | Inhibitors of slow reacting substance of anaphylaxis | SCHERING CORPORATION (US) | 1988-07-19 | — | — | US | disclosed |
| US-4696946-A | Topical Treatment of hyperproliferative skin diseases | SCHERING CORPORATION (US) | 1987-09-29 | — | — | US | disclosed |