SCHEMBL9860201

SCHEMBL9860201

COc1cccc2cc(CC(C)=O)ccc12

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.50
KDM4E B2RXH2 1/20 0.50
HPGD P15428 1/20 0.50
HSD17B10 Q99714 1/20 0.50
DHODH Q02127 1/20 0.46
LMNA P02545 2/20 0.46
RECQL P46063 1/20 0.46
GAA P10253 2/20 0.45
KMT2A Q03164 2/20 0.45
MEN1 O00255 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.43
CYP3A4 P08684 1/20 0.42
AKR1B1 P15121 1/20 0.42
PTGS1 P23219 1/20 0.42
AKR1C3 P42330 1/20 0.42
AKR1C2 P52895 1/20 0.42
TSHR P16473 1/20 0.42
NFKB1 P19838 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
POLB P06746 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31074309 0.88 GAA (0.60) ALDH1A1KDM4EHPGDHSD17B10DHODH
SCHEMBL11741419 0.88 GAA (0.60) ALDH1A1KDM4EHPGDHSD17B10DHODH
Methane SCHEMBL11358776 0.87 GAA (0.59) ALDH1A1KDM4EHPGDHSD17B10DHODH
SCHEMBL7758275 0.85 NPC1 (0.58) ALDH1A1KDM4EHPGDHSD17B10DHODH
SCHEMBL27808525 0.83 KMT2A (0.50) ALDH1A1KDM4EHPGDHSD17B10DHODH
SCHEMBL18789582 0.80 CYP1A2 (0.50) ALDH1A1HPGDHSD17B10L3MBTL1AKR1B1
SCHEMBL28061486 0.79 NCEH1 (0.50) ALDH1A1KDM4ELMNAGAACYP3A4
SCHEMBL27727477 0.79 DHODH (0.49) ALDH1A1KDM4EHPGDHSD17B10DHODH
SCHEMBL2665741 0.79 CYP1A2 (0.50) ALDH1A1KDM4EHPGDHSD17B10DHODH
SCHEMBL21241116 0.78 AKR1B1 (0.44) ALDH1A1KDM4EHPGDHSD17B10GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0424242-A2 Process for preparing carboxylic acids by means of oxidation of corresponding aldehydes L'AIR LIQUIDE, SOCIETE ANONYME POUR L'ETUDE ET L'EXPLOITATION DES PROCEDES GEORGES CLAUDE (FR) 1991-04-24 EP disclosed