Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCEH1 | Q6PIU2 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11742127 | 0.89 | GAA (0.61) | NCEH1GAACYP19A1CYP11B1CYP11B2 | |
| SCHEMBL11743240 | 0.87 | NCEH1 (0.52) | NCEH1GAACYP19A1CYP11B1CYP11B2 | |
| SCHEMBL1574663 | 0.86 | NCEH1 (0.48) | NCEH1GAACYP19A1CYP11B1CYP11B2 | |
| SCHEMBL13781590 | 0.81 | NCEH1 (0.54) | NCEH1GAACYP19A1CYP3A4SLC6A2 | |
| SCHEMBL11078619 | 0.79 | NCEH1 (0.46) | NCEH1GAACYP19A1CYP11B1CYP11B2 | |
| SCHEMBL9860201 | 0.79 | ALDH1A1 (0.50) | GAAPTGS1AKR1C3AKR1C2CYP3A4 | |
| SCHEMBL13781586 | 0.79 | LDHA (0.52) | NCEH1GAACYP19A1CYP11B1CYP11B2 | |
| SCHEMBL4086439 | 0.79 | ALDH1A1 (0.53) | GAACYP3A4LMNATP53CYP1A2 | |
| SCHEMBL11078616 | 0.78 | ALDH1A1 (0.53) | NCEH1GAACYP19A1CYP11B1CYP11B2 | |
| SCHEMBL18255551 | 0.77 | GAA (0.75) | GAACYP19A1CYP3A4LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106397154-A | Synthetic method of 1-(5-chloro-6-methoxyl-2-naphthyl)acetone serving as naproxen medicinal intermediate | 厦门安普顿信息科技有限公司 | 2017-02-15 | — | — | CN | disclosed |
| CN-106397154-A | Synthetic method of 1-(5-chloro-6-methoxyl-2-naphthyl)acetone serving as naproxen medicinal intermediate | 厦门安普顿信息科技有限公司 | 2017-02-15 | — | — | CN | disclosed |
| CN-105481664-A | Synthetic method of naproxen drug intermediate 1-(5-chloro-6-methoxyl-2-naphthyl) acetone | CHENGDU DONGDIAN AIER SCIENCE AND TECH CO LTD | 2016-04-13 | — | — | CN | disclosed |
| CN-105481664-A | Synthetic method of naproxen drug intermediate 1-(5-chloro-6-methoxyl-2-naphthyl) acetone | CHENGDU DONGDIAN AIER SCIENCE AND TECH CO LTD | 2016-04-13 | — | — | CN | disclosed |