Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 4/20 | 0.57 |
| ▸ | PHF8 | Q9UPP1 | 4/20 | 0.57 |
| ▸ | KDM2A | Q9Y2K7 | 4/20 | 0.57 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.57 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.57 |
| ▸ | KDM4A | O75164 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9860329 | 1.00 | KDM5A (0.57) | KDM5APHF8KDM2AKDM4CKDM7A | |
| SCHEMBL9859913 | 1.00 | KDM5A (0.57) | KDM5APHF8KDM2AKDM4CKDM7A | |
| SCHEMBL9860024 | 1.00 | KDM5A (0.57) | KDM5APHF8KDM2AKDM4CKDM7A | |
| SCHEMBL9859860 | 1.00 | KDM5A (0.57) | KDM5APHF8KDM2AKDM4CKDM7A | |
| SCHEMBL9859864 | 1.00 | KDM5A (0.57) | KDM5APHF8KDM2AKDM4CKDM7A | |
| SCHEMBL28622817 | 0.92 | KDM5A (0.47) | KDM5APHF8KDM2AKDM4CKDM7A | |
| SCHEMBL4449247 | 0.92 | KDM5A (0.65) | KDM5APHF8KDM2AKDM4CKDM7A | |
| SCHEMBL16046794 | 0.92 | KDM5A (0.65) | KDM5APHF8KDM2AKDM4CKDM7A | |
| SCHEMBL826408 | 0.92 | KDM5A (0.65) | KDM5APHF8KDM2AKDM4CKDM7A | |
| SCHEMBL4978263 | 0.92 | KDM5A (0.65) | KDM5APHF8KDM2AKDM4CKDM7A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0201196-B1 | BENZOQUINONE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1991-07-03 | — | — | EP | disclosed |
| US-4897420-A | ISCHEMIC DISEASES; ANTIALLERGENS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-01-30 | — | — | US | disclosed |
| EP-0201196-A2 | Benzoquinone derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1986-11-12 | — | — | EP | disclosed |