Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.41 |
| ▸ | MITF | O75030 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 6/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5725637 | 0.93 | MEN1 (0.50) | MEN1KMT2ASMN1; SMN2MITFALDH1A1 | |
| SCHEMBL21886902 | 0.85 | SLC6A3 (0.53) | MEN1KMT2AALDH1A1SLC6A3KDM4C | |
| SCHEMBL22504269 | 0.85 | KMT2A (0.52) | MEN1KMT2ASLC6A3KDM4CTDP1 | |
| SCHEMBL21886901 | 0.84 | MEN1 (0.49) | MEN1KMT2AALDH1A1HTTRAB9A | |
| SCHEMBL9860590 | 0.84 | SMN1; SMN2 (0.52) | MEN1KMT2ASMN1; SMN2MITFALDH1A1 | |
| SCHEMBL21374326 | 0.82 | MEN1 (0.49) | MEN1KMT2AALDH1A1RAB9ASLC6A3 | |
| SCHEMBL9860310 | 0.79 | MEN1 (0.53) | MEN1KMT2ASMN1; SMN2MITFALDH1A1 | |
| SCHEMBL5726231 | 0.79 | KMT2A (0.53) | MEN1KMT2ASMN1; SMN2MITFALDH1A1 | |
| SCHEMBL5725306 | 0.78 | KMT2A (0.52) | MEN1KMT2ASMN1; SMN2MITFALDH1A1 | |
| SCHEMBL17846111 | 0.77 | MEN1 (0.48) | MEN1KMT2AALDH1A1RAB9ASLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4996225-A | Antitumor agents | FARMOS GROUP LTD. (FI) | 1991-02-26 | — | — | US | disclosed |
| US-4696949-A | ANTITUMOR AGENTS, ANTIESTROGENS | FARMOS GROUP LTD. (FI) | 1987-09-29 | — | — | US | disclosed |
| EP-0095875-A2 | Novel tri-phenyl alkane and alkene derivatives and their preparation and use | Farmos Group Ltd. (FI) | 1983-12-07 | — | — | EP | disclosed |