Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 7/20 | 0.48 |
| ▸ | GABRG2 | P18507 | 7/20 | 0.48 |
| ▸ | GABRB3 | P28472 | 7/20 | 0.48 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.48 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9860364 | 1.00 | GABRA1 (0.48) | GABRA1GABRG2GABRB3GABRB2GABRB1 | |
| SCHEMBL9190963 | 0.80 | POLB (0.55) | GABRA1GABRG2GABRB3GABRB2GABRB1 | |
| SCHEMBL4468677 | 0.80 | POLB (0.55) | GABRA1GABRG2GABRB3GABRB2GABRB1 | |
| SCHEMBL4468681 | 0.80 | POLB (0.55) | GABRA1GABRG2GABRB3GABRB2GABRB1 | |
| SCHEMBL9860358 | 0.79 | NPC1 (0.38) | ALDH1A1KDM4ETSHRSMN1; SMN2MAPT | |
| SCHEMBL9860429 | 0.79 | NPC1 (0.38) | ALDH1A1KDM4ETSHRSMN1; SMN2MAPT | |
| SCHEMBL9860377 | 0.73 | MEN1 (0.41) | GABRA1GABRG2GABRB3GABRB2GABRB1 | |
| SCHEMBL9860375 | 0.73 | MEN1 (0.41) | GABRA1GABRG2GABRB3GABRB2GABRB1 | |
| SCHEMBL7944695 | 0.73 | TSHR (0.53) | ALDH1A1KDM4ETSHRCASP1SMN1; SMN2 | |
| SCHEMBL8065539 | 0.72 | SMN1; SMN2 (0.71) | ALDH1A1KDM4ETSHRCASP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4990646-A | Preparation of halogenated quinolonecarboxylic acids | BAYER AKTIENGESELLSCHAFT (DE) | 1991-02-05 | — | — | US | claimed |
| EP-0168737-A2 | Process for the preparation of halogenated quinolinoncarboxylic acids | BAYER AG (DE) | 1986-01-22 | — | — | EP | claimed |
| US-4990646-A | Preparation of halogenated quinolonecarboxylic acids | BAYER AKTIENGESELLSCHAFT (DE) | 1991-02-05 | — | — | US | disclosed |
| US-4914228-A | Preparation of halogenated quinolonecarboxylic acids | BAYER AKTIENGESELLSCHAFT (DE) | 1990-04-03 | — | — | US | disclosed |
| US-4782156-A | Nitriles of halogenated quinolonecarboxylic acids | BAYER AKTIENGESELLSCHAFT (DE) | 1988-11-01 | — | — | US | disclosed |
| US-4680401-A | Preparation of halogenated quinolonecarboxylic acids | BAYER AKTIENGESELLSCHAFT (DE) | 1987-07-14 | — | — | US | disclosed |
| EP-0168737-A2 | Process for the preparation of halogenated quinolinoncarboxylic acids | BAYER AG (DE) | 1986-01-22 | — | — | EP | disclosed |