Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | PKM | P14618 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16397410 | 0.82 | NPSR1 (0.50) | NPSR1ALDH1A1KDM4EPKML3MBTL1 | |
| SCHEMBL18974159 | 0.82 | NPSR1 (0.50) | NPSR1ALDH1A1KDM4EPKML3MBTL1 | |
| SCHEMBL12228844 | 0.82 | NPSR1 (0.50) | NPSR1ALDH1A1KDM4EPKML3MBTL1 | |
| SCHEMBL30862551 | 0.81 | NPSR1 (0.48) | NPSR1ALDH1A1KDM4EPKML3MBTL1 | |
| SCHEMBL2474815 | 0.81 | NPSR1 (0.48) | NPSR1ALDH1A1KDM4EPKML3MBTL1 | |
| SCHEMBL11917066 | 0.81 | NPSR1 (0.48) | NPSR1ALDH1A1KDM4EPKML3MBTL1 | |
| SCHEMBL31539265 | 0.81 | NPSR1 (0.48) | NPSR1ALDH1A1KDM4EPKML3MBTL1 | |
| SCHEMBL3046694 | 0.81 | KDM4E (0.59) | NPSR1ALDH1A1KDM4EPKML3MBTL1 | |
| SCHEMBL26281746 | 0.81 | NPSR1 (0.48) | NPSR1ALDH1A1KDM4EPKML3MBTL1 | |
| SCHEMBL9860567 | 0.79 | ALDH1A1 (0.36) | NPSR1ALDH1A1KDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105209446-A | GPR120 agonists for the treatment of type ii diabetes | JANSSEN PHARMACEUTICA NV | 2015-12-30 | — | — | CN | disclosed |
| US-5068343-A | Fungicides for plants | BAYER AKTIENGESELLSCHAFT (DE) | 1991-11-26 | — | — | US | disclosed |