Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.68 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.68 |
| ▸ | ESR1 | P03372 | 7/20 | 0.58 |
| ▸ | ESRRG | P62508 | 16/20 | 0.57 |
| ▸ | ESRRB | O95718 | 7/20 | 0.55 |
| ▸ | ESRRA | P11474 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20842111 | 0.91 | ESR1 (0.73) | ESR1ESRRGESRRB | |
| SCHEMBL1151938 | 0.91 | ESR1 (0.73) | ESR1ESRRGESRRB | |
| SCHEMBL1151939 | 0.91 | ESR1 (0.73) | ESR1ESRRGESRRB | |
| SCHEMBL9100272 | 0.86 | PTGS2 (0.61) | PTGS2ESR2ESR1ESRRGESRRB | |
| SCHEMBL24354499 | 0.83 | ESR1 (0.68) | ESR1ESRRGESRRB | |
| SCHEMBL28108412 | 0.81 | PTGS2 (1.00) | PTGS2ESR2ESR1 | |
| SCHEMBL28227677 | 0.79 | PTGS2 (0.89) | PTGS2ESR2ESR1 | |
| SCHEMBL24505427 | 0.78 | ESRRG (0.72) | ESR1ESRRGESRRB | |
| SCHEMBL2229348 | 0.78 | ESR1 (0.71) | ESR2ESR1ESRRGESRRB | |
| SCHEMBL1151987 | 0.78 | ESR1 (0.71) | ESR2ESR1ESRRGESRRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4996225-A | Antitumor agents | FARMOS GROUP LTD. (FI) | 1991-02-26 | — | — | US | disclosed |
| US-4696949-A | ANTITUMOR AGENTS, ANTIESTROGENS | FARMOS GROUP LTD. (FI) | 1987-09-29 | — | — | US | disclosed |
| EP-0095875-B1 | NOVEL TRI-PHENYL ALKANE AND ALKENE DERIVATIVES AND THEIR PREPARATION AND USE | Farmos Group Ltd. (FI) | 1986-09-10 | — | — | EP | disclosed |
| EP-0095875-A2 | Novel tri-phenyl alkane and alkene derivatives and their preparation and use | Farmos Group Ltd. (FI) | 1983-12-07 | — | — | EP | disclosed |