Acrolein

Acrolein

SCHEMBL9860799

C=CC=O.O=CCCO

nearest known ligand 0.00

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⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glycerin SCHEMBL3426756 0.86 ALDH1A1 (0.39)
SCHEMBL9249312 0.84 HIF1A (0.47)
SCHEMBL50638 0.84
SCHEMBL16859756 0.81
SCHEMBL16288075 0.81
SCHEMBL6435115 0.81
SCHEMBL28222197 0.81
Water SCHEMBL728694 0.81
Water SCHEMBL22031592 0.81
SCHEMBL29269061 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112939810-B Method for synthesizing acrylonitrile by ammoxidation of acrolein 上海师范大学 2023-05-16 CN disclosed
EP-3204367-A1 IMPROVED 5-HYDROXYMETHYLFURFURAL PRODUCTION USING A MULTI-FLUORINATED ALCOHOL COMPOUND Vorlop, Klaus-Dieter (DE) 2017-08-16 EP disclosed
WO-2016055608-A1 IMPROVED 5-HYDROXYMETHYLFURFURAL PRODUCTION USING A MULTI-FLUORINATED ALCOHOL COMPOUND VORLOP KLAUS-DIETER (DE) 2016-04-14 WO disclosed
US-5015789-A Multistage synthesis of propanediol from hydration of acrolein and hydrogenation of 3-hydroxypropionaldehyde DEGUSSA AKTIENGESELLSCHAFT (DE) 1991-05-14 US disclosed
EP-0412337-A2 Method for the production of 1,3-propandiol Degussa Aktiengesellschaft (DE) 1991-02-13 EP disclosed