SCHEMBL9860813

SCHEMBL9860813

C=C(C)C(C)(Cl)C(=O)CC

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.35
TDP1 Q9NUW8 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20917016 0.75 TDP1 (0.38) ALDH1A1TDP1
SCHEMBL9860804 0.74
SCHEMBL9766511 0.71 ALDH1A1 (0.41) ALDH1A1
SCHEMBL29194757 0.71
SCHEMBL28050060 0.71
SCHEMBL509484 0.70 ALDH1A1 (0.41) ALDH1A1TDP1
SCHEMBL14523829 0.68 ALDH1A1 (0.32) ALDH1A1TDP1
SCHEMBL5325238 0.68
Trichloroethane SCHEMBL27849782 0.68 ALDH1A1 (0.67) ALDH1A1TDP1
SCHEMBL11457278 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5026918-A Synthesis of 2,3,5-trisubstituted-2-cyclopentenones via base induced cyclization of alpha-chloro unsaturated ketones PETROLITE CORPORATION (US) 1991-06-25 US disclosed