Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8259225 | 0.79 | — | — | |
| SCHEMBL7499829 | 0.77 | — | — | |
| SCHEMBL7499836 | 0.77 | — | — | |
| SCHEMBL10965368 | 0.73 | — | — | |
| SCHEMBL11093784 | 0.72 | — | — | |
| SCHEMBL16315614 | 0.72 | SMN1; SMN2 (0.30) | — | |
| SCHEMBL7501306 | 0.71 | — | — | |
| SCHEMBL7501312 | 0.71 | — | — | |
| SCHEMBL10540453 | 0.71 | — | — | |
| SCHEMBL6963835 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4994568-A | Intermediates for 6-,1- and 2-substituted carbapenem antibiotics | MERCK & CO., INC. (US) | 1991-02-19 | — | — | US | disclosed |
| EP-0030031-B1 | 6-(1-HYDROXYETHYL)-2-(2-AMINOETHYLTHIO)-1,1-DISUBSTITUTED-1-CARBADETHIAPEN-2-EM-3-CARBOXYLIC ACIDS, A PROCESS FOR PREPARING THE SAME, AN ANTIBIOTIC PHARMACEUTICAL COMPOSITION COMPRISING THE SAME, INTERMEDIATES USEFUL IN A SYNTHESIS OF THAT KIND AND PROCESSES FOR PREPARING INTERMEDIATES SUITABLE FOR THE SYNTHESIS OF THAT KIND | MERCK & CO. INC. (US) | 1986-09-17 | — | — | EP | disclosed |
| EP-0030032-B1 | 6-, 1- AND 2-SUBSTITUTED-1-CARBADETHIAPEN-2-EM-3-CARBOXYLIC ACIDS, PROCESSES FOR PREPARING THE SAME, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME, AND INTERMEDIATES | MERCK & CO. INC. (US) | 1986-08-27 | — | — | EP | disclosed |
| US-4600713-A | CARBAPENICILLIN ANTIBIOTICS | MERCK & CO., INC. (US) | 1986-07-15 | — | — | US | disclosed |
| US-4582643-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1986-04-15 | — | — | US | disclosed |
| US-4350631-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1982-09-21 | — | — | US | disclosed |
| EP-0060077-A1 | Beta-lactam antibiotics, their preparation and use | BEECHAM GROUP PLC (GB) | 1982-09-15 | — | — | EP | disclosed |
| US-4341706-A | Process for the preparation of carbapenem antibiotics | MERCK & CO., INC. (US) | 1982-07-27 | — | — | US | disclosed |
| EP-0054917-A2 | 6- and 4-Substituted-1-azabicyclo(3.2.0)heptan-3,7-dione-2-carboxylates | MERCK & CO. INC. (US) | 1982-06-30 | — | — | EP | disclosed |
| US-4312871-A | 6-, 1- And 2-substituted-1-carbadethiapen-2-em-3-carboxylic acids | MERCK & CO., INC. (US) | 1982-01-26 | — | — | US | disclosed |
| EP-0030031-A2 | 6-(1-Hydroxyethyl)-2-(2-aminoethylthio)-1,1-disubstituted-1-carbadethiapen-2-em-3-carboxylic acids, a process for preparing the same, an antibiotic pharmaceutical composition comprising the same, intermediates useful in a synthesis of that kind and processes for preparing intermediates suitable for the synthesis of that kind | MERCK & CO. INC. (US) | 1981-06-10 | — | — | EP | disclosed |
| US-4262010-A | THIENAMYCIN-RELATED ANTIBIOTICS | MERCK & CO., INC. (US) | 1981-04-14 | — | — | US | disclosed |
| US-4262009-A | AMINO ACID DERIVATIVE ANTIBIOTICS | MERCK & CO., INC. (US) | 1981-04-14 | — | — | US | disclosed |