SCHEMBL9861008

SCHEMBL9861008

C=CCc1ccccc1OC(=O)/C=C/C(=O)O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.49
MAPT P10636 1/20 0.49
HPGD P15428 1/20 0.49
HSD17B10 Q99714 1/20 0.49
AKR1C3 P42330 1/20 0.47
AKR1C2 P52895 1/20 0.47
THRA P10827 1/20 0.45
THRB P10828 1/20 0.45
HCAR2 Q8TDS4 2/20 0.44
ELANE P08246 1/20 0.42
ALDH1A1 P00352 1/20 0.41
ADRB2 P07550 3/20 0.39
ADRB1 P08588 3/20 0.39
HRH1 P35367 2/20 0.39
LMNA P02545 1/20 0.39
HTR1A P08908 1/20 0.39
ADRB3 P13945 1/20 0.39
ADRA2C P18825 1/20 0.39
SLC6A2 P23975 1/20 0.39
BDKRB2 P30411 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9860308 1.00 KDM4E (0.49) KDM4EMAPTHPGDHSD17B10AKR1C3
SCHEMBL9860298 1.00 KDM4E (0.49) KDM4EMAPTHPGDHSD17B10AKR1C3
SCHEMBL9861004 0.94 KDM4E (0.50) KDM4EMAPTHPGDHSD17B10AKR1C3
SCHEMBL9860292 0.94 KDM4E (0.50) KDM4EMAPTHPGDHSD17B10AKR1C3
SCHEMBL5914446 0.87 KDM4E (0.42) KDM4EMAPTHPGDHSD17B10AKR1C3
SCHEMBL5914449 0.87 KDM4E (0.42) KDM4EMAPTHPGDHSD17B10AKR1C3
SCHEMBL311912 0.84 THRA (0.60) KDM4ETHRATHRBELANEALDH1A1
SCHEMBL9177896 0.83 KDM4E (0.53) KDM4EMAPTHPGDHSD17B10THRA
SCHEMBL1362785 0.83 KDM4E (0.49) KDM4ETHRATHRBELANEALDH1A1
SCHEMBL9177888 0.83 KDM4E (0.53) KDM4EMAPTHPGDHSD17B10THRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0233299-B1 OPTICAL RESIN AND PROCESS FOR PREPARING THE SAME NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1991-03-13 EP claimed
US-4855374-A Optical resin from diallyl esters NIPPON OIL AND FATS CO., LTD. (JP) 1989-08-08 US claimed
EP-0233299-A1 Optical resin and process for preparing the same NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1987-08-26 EP claimed
EP-0233299-B1 OPTICAL RESIN AND PROCESS FOR PREPARING THE SAME NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1991-03-13 EP disclosed
US-4855374-A Optical resin from diallyl esters NIPPON OIL AND FATS CO., LTD. (JP) 1989-08-08 US disclosed
EP-0233299-A1 Optical resin and process for preparing the same NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1987-08-26 EP disclosed