Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC15A1 | P46059 | 1/20 | 0.54 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.53 |
| ▸ | ALPI | P09923 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | XIAP | P98170 | 1/20 | 0.53 |
| ▸ | LTA4H | P09960 | 2/20 | 0.51 |
| ▸ | CPA3 | P15088 | 1/20 | 0.44 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.43 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.43 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.43 |
| ▸ | MC4R | P32245 | 1/20 | 0.42 |
| ▸ | MC5R | P33032 | 1/20 | 0.42 |
| ▸ | MC3R | P41968 | 1/20 | 0.42 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | CTSC | P53634 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3259767 | 0.83 | ALPI (0.49) | SLC15A1SLC7A5ALPIPKMPTGS1 | |
| SCHEMBL8821943 | 0.80 | SLC15A1 (0.52) | SLC15A1SLC7A5ALPIPKMPTGS1 | |
| SCHEMBL10584413 | 0.79 | SLC7A5 (0.62) | SLC15A1SLC7A5ALPIPKMPTGS1 | |
| SCHEMBL9716075 | 0.78 | ALPI (0.49) | SLC15A1SLC7A5ALPIPKMPTGS1 | |
| SCHEMBL5691566 | 0.77 | ALPI (0.42) | SLC15A1SLC7A5ALPIPKMPTGS1 | |
| SCHEMBL4481943 | 0.77 | ALPI (0.42) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL28417004 | 0.77 | ALPI (0.42) | SLC15A1SLC7A5ALPIPKMPTGS1 | |
| SCHEMBL27652945 | 0.77 | SLC15A1 (0.52) | SLC15A1SLC7A5ALPIPKMPTGS1 | |
| SCHEMBL28440257 | 0.75 | SLC7A5 (0.57) | SLC15A1SLC7A5ALPIPKMPTGS1 | |
| SCHEMBL28440256 | 0.75 | SLC7A5 (0.57) | SLC15A1SLC7A5ALPIPKMPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0415693-A1 | Composition and method for selective enhancement of opiate activity and reduction of opiate tolerance and dependence | ARIZONA TECHNOLOGY DEVELOPMENT CORPORATION (US) | 1991-03-06 | — | — | EP | disclosed |