SCHEMBL9861369

SCHEMBL9861369

O=S(O)(=S)OCc1cccc(F)c1

nearest known ligand 0.56

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.56
AGXT P21549 2/20 0.56
NR4A2 P43354 2/20 0.47
HCAR2 Q8TDS4 1/20 0.47
MAOB P27338 11/20 0.46
PARP10 Q53GL7 1/20 0.46
MMP1 P03956 1/20 0.43
MMP2 P08253 1/20 0.43
MMP9 P14780 1/20 0.43
MMP12 P39900 1/20 0.43
MAOA P21397 2/20 0.43
KDM4E B2RXH2 1/20 0.43
CYP1A2 P05177 1/20 0.43
CYP2D6 P10635 1/20 0.43
MAPT P10636 1/20 0.43
CYP2C9 P11712 1/20 0.43
CYP2C19 P33261 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL775797 0.82 IDO1 (0.58) IDO1AGXTNR4A2HCAR2MAOB
SCHEMBL9861115 0.81 CYP3A4 (0.58) IDO1AGXTNR4A2HCAR2MAOB
SCHEMBL9861770 0.80 IDO1 (0.56) IDO1MAOBMMP2MMP9MMP12
SCHEMBL778647 0.79 IDO1 (0.55) IDO1AGXTNR4A2HCAR2MAOB
SCHEMBL28736694 0.79 IDO1 (0.55) IDO1AGXTNR4A2HCAR2MAOB
SCHEMBL10859327 0.79 IDO1 (0.50) IDO1AGXTNR4A2MAOBPARP10
SCHEMBL9861104 0.79 AGXT (0.57) AGXTNR4A2MMP1MMP2MMP9
Ammonia Solution, Strong SCHEMBL28883022 0.79 IDO1 (0.50) IDO1AGXTNR4A2HCAR2MAOB
SCHEMBL5078811 0.78 CA2 (0.59) IDO1AGXTMMP1MMP2MMP9
SCHEMBL777170 0.78 IDO1 (0.53) IDO1AGXTNR4A2HCAR2MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113651863-B Unsaturated thioglycoside compound and selective synthesis method and application thereof 华东师范大学 2023-11-10 CN disclosed
CN-113651863-A Unsaturated thioglycoside compound and selective synthesis method and application thereof 华东师范大学 2021-11-16 CN disclosed
EP-0150168-B1 USE OF METAL SALTS OF THIOSULPHURIC -S-ESTERS AS RUBBER/METAL BONDING PROMOTERS MONSANTO EUROPE S.A./N.V. (BE) 1991-05-08 EP disclosed
US-4581297-A STEEL BELTED RADIAL TIRES MONSANTO EUROPE, S.A. (BE) 1986-04-08 US disclosed
EP-0150168-A2 Use of metal salts of thiosulphuric -S-esters as rubber/metal bonding promoters MONSANTO EUROPE S.A./N.V. (BE) 1985-07-31 EP disclosed