Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 3/20 | 0.49 |
| ▸ | PNMT | P11086 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.42 |
| ▸ | RBP4 | P02753 | 4/20 | 0.41 |
| ▸ | CUL4A | Q13619 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 3/20 | 0.38 |
| ▸ | FEN1 | P39748 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29721046 | 0.81 | HTR2C (0.70) | HTR2CGAATDP1RBP4CUL4A | |
| SCHEMBL1919230 | 0.81 | HTR2C (0.70) | HTR2CGAATDP1RBP4CUL4A | |
| SCHEMBL11567722 | 0.80 | TDO2 (0.42) | HTR2CFEN1 | |
| SCHEMBL29720917 | 0.79 | HTR2C (0.68) | HTR2CGAATDP1RBP4CUL4A | |
| SCHEMBL15156609 | 0.79 | HTR2C (0.68) | HTR2CGAATDP1RBP4CUL4A | |
| SCHEMBL2783896 | 0.79 | DRD3 (0.45) | HTR2CPNMTRBP4 | |
| SCHEMBL9861616 | 0.79 | GAA (0.49) | HTR2CPNMTGAATDP1CHRNB2 | |
| SCHEMBL10627728 | 0.78 | TDO2 (0.44) | FEN1 | |
| SCHEMBL28773240 | 0.78 | TDO2 (0.44) | FEN1 | |
| SCHEMBL28247607 | 0.77 | HTR2C (0.70) | HTR2CGAATDP1RBP4CUL4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5008425-A | Trifluoromethylation of carbonyl compounds | ETHYL CORPORATION (US) | 1991-04-16 | — | — | US | disclosed |
| EP-0336371-A2 | Gem-disubstituted cyclohexadienones and their production | ETHYL CORPORATION (US) | 1989-10-11 | — | — | EP | disclosed |
| US-4871877-A | Gem-disubstituted cyclohexadienones and their production | ETHYL CORPORATION (US) | 1989-10-03 | — | — | US | disclosed |
| US-4845258-A | Production of gem-disubstituted cyclohexadienones | ETHYL CORPORATION (US) | 1989-07-04 | — | — | US | disclosed |
| US-4804774-A | Production of gem-disubstituted cyclohexadienones | ETHYL CORPORATION (US) | 1989-02-14 | — | — | US | disclosed |
| US-4804772-A | Gem-disubstituted cyclohexadienones and their production | ETHYL CORPORATION (US) | 1989-02-14 | — | — | US | disclosed |
| US-4804773-A | Production of gem-disubstituted cyclohexadienones | ETHYL CORPORATION (US) | 1989-02-14 | — | — | US | disclosed |