SCHEMBL9861470

SCHEMBL9861470

CCCCCCCCCCCCSCC[Si](C)(OCC)OCC

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRKD3 O94806 3/20 0.38
PRKCG P05129 3/20 0.38
PRKCB P05771 3/20 0.38
PRKCA P17252 3/20 0.38
PRKCH P24723 3/20 0.38
PRKCI P41743 3/20 0.38
PRKCE Q02156 3/20 0.38
PRKCQ Q04759 3/20 0.38
PRKCZ Q05513 3/20 0.38
PRKCD Q05655 3/20 0.38
PRKD1 Q15139 3/20 0.38
CES2 O00748 3/20 0.37
MAPT P10636 2/20 0.37
GMNN O75496 1/20 0.37
TP53 P04637 1/20 0.37
POLB P06746 1/20 0.37
THRB P10828 1/20 0.37
CYP2C9 P11712 1/20 0.37
BLM P54132 1/20 0.37
HSD17B10 Q99714 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29240701 0.92 PRKD3 (0.38) PRKD3PRKCGPRKCBPRKCAPRKCH
SCHEMBL28551827 0.82 CES2 (0.38) PRKD3PRKCGPRKCBPRKCAPRKCH
SCHEMBL3923447 0.81
SCHEMBL29240677 0.81 CES2 (0.37) PRKD3PRKCGPRKCBPRKCAPRKCH
SCHEMBL12972119 0.80
SCHEMBL29240746 0.79 CES2 (0.36) PRKD3PRKCGPRKCBPRKCAPRKCH
SCHEMBL29240724 0.79 CES2 (0.36) PRKD3PRKCGPRKCBPRKCAPRKCH
SCHEMBL23658245 0.79 TSHR (0.40) THRBHSD17B10ALDH1A1LMNATSHR
SCHEMBL17191748 0.79 TSHR (0.40) THRBHSD17B10ALDH1A1LMNATSHR
SCHEMBL8852535 0.79 TSHR (0.40) THRBHSD17B10ALDH1A1LMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0197540-B1 USE OF AMINES FOR STABILIZING POLYSILOXANE FLUIDS WACKER-CHEMIE GMBH (DE) 1991-11-13 EP disclosed
US-4622412-A Process for preparation of mercapto silicone fluid GENESEE POLYMERS CORPORATION, A CORP. OF MI 1986-11-11 US disclosed
EP-0197540-A2 Use of amines for stabilizing polysiloxane fluids WACKER-CHEMIE GMBH (DE) 1986-10-15 EP disclosed
US-4612055-A Stabilized blends of thiofunctional polysiloxane fluids and organopolysiloxane fluids and a process for stabilizing the same SWS SILICONES CORPORATION (US) 1986-09-16 US disclosed
US-4588771-A Stabilized thiofunctional polysiloxane fluids and a process for stabilizing the same SWS SILICONES CORPORATION (US) 1986-05-13 US disclosed
EP-0034191-A1 Process for preparing thiofunctional polysiloxane polymers and products obtained thereby SWS Silicones Corporation (US) 1981-08-26 EP disclosed
US-4251277-A CORROSION INHIBITORS, RELEASE AGENTS SWS SILICONES CORPORATION (US) 1981-02-17 US disclosed
US-4230816-A Thiofunctional polysiloxane polymers SWS SILICONES CORPORATION (US) 1980-10-28 US disclosed
US-4046795-A Process for preparing thiofunctional polysiloxane polymers SWS SILICONES CORPORATION (US) 1977-09-06 US disclosed