Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 6/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9550986 | 0.90 | HSD17B10 (0.54) | MAPTALDH1A1CYP3A4CYP1A2CYP2C9 | |
| SCHEMBL38925 | 0.90 | HSD17B10 (0.54) | MAPTALDH1A1CYP3A4CYP1A2CYP2C9 | |
| SCHEMBL651427 | 0.90 | HSD17B10 (0.54) | MAPTALDH1A1CYP3A4CYP1A2CYP2C9 | |
| SCHEMBL18241644 | 0.88 | HSD17B10 (0.58) | MAPTALDH1A1CYP3A4ALOX12HTT | |
| Ammonia Solution, Strong SCHEMBL27625138 | 0.88 | HSD17B10 (0.52) | MAPTALDH1A1CYP3A4CYP1A2CYP2C9 | |
| SCHEMBL1727316 | 0.88 | HSD17B10 (0.58) | MAPTALDH1A1CYP3A4ALOX12HTT | |
| SCHEMBL23802675 | 0.87 | MAPT (0.42) | MAPTALDH1A1CYP3A4CYP1A2CYP2C9 | |
| Naphthalene SCHEMBL3868843 | 0.85 | HSD17B10 (0.48) | MAPTALDH1A1CYP3A4CYP1A2CYP2C9 | |
| SCHEMBL7775804 | 0.84 | MAPT (0.48) | MAPTALDH1A1CYP3A4CYP1A2CYP2C9 | |
| SCHEMBL29755964 | 0.83 | MAPT (0.56) | MAPTALDH1A1CYP3A4CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5070158-A | Covalently labeled siloxane polymers | HEWLETT-PACKARD COMPANY (US) | 1991-12-03 | — | — | US | disclosed |
| EP-0283206-A2 | Covalently labeled siloxane polymers | Hewlett-Packard Company (US) | 1988-09-21 | — | — | EP | disclosed |