SCHEMBL7775804

SCHEMBL7775804

Nc1ccc(-c2ccc(Nc3ccccc3)c(-c3ccccc3)c2-c2ccccc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 10/20 0.48
ALDH1A1 P00352 8/20 0.48
L3MBTL1 Q9Y468 4/20 0.48
CYP1A2 P05177 3/20 0.48
CYP2C9 P11712 3/20 0.48
HTT P42858 2/20 0.48
CYP3A4 P08684 2/20 0.48
CYP2C19 P33261 2/20 0.48
ALOX12 P18054 1/20 0.48
GAA P10253 8/20 0.47
TDP1 Q9NUW8 5/20 0.47
ALOX15 P16050 3/20 0.47
HSD17B10 Q99714 4/20 0.44
TAAR1 Q96RJ0 1/20 0.44
KDM4E B2RXH2 8/20 0.43
HPGD P15428 2/20 0.43
TP53 P04637 1/20 0.43
APP P05067 1/20 0.43
SNCA P37840 1/20 0.43
BLM P54132 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29755964 0.95 MAPT (0.56) MAPTALDH1A1L3MBTL1CYP1A2CYP2C9
SCHEMBL28016764 0.91 MAPT (0.44) MAPTALDH1A1L3MBTL1CYP1A2CYP2C9
SCHEMBL28048060 0.89 MAPT (0.41) MAPTALDH1A1L3MBTL1CYP1A2CYP2C9
SCHEMBL7759493 0.87 MAPT (0.40) MAPTALDH1A1L3MBTL1CYP1A2CYP2C9
SCHEMBL31265542 0.87 ALDH1A1 (0.45) MAPTALDH1A1L3MBTL1CYP1A2CYP2C9
SCHEMBL3461985 0.86 NPSR1 (0.46) MAPTALDH1A1L3MBTL1HTTGAA
SCHEMBL10707344 0.86 MAPT (0.44) MAPTALDH1A1L3MBTL1CYP1A2CYP2C9
SCHEMBL28133683 0.86 ALDH1A1 (0.51) MAPTALDH1A1L3MBTL1CYP1A2CYP2C9
Diphenylamine SCHEMBL9861503 0.84 MAPT (0.53) MAPTALDH1A1L3MBTL1CYP1A2CYP2C9
SCHEMBL29755945 0.84 MAPT (0.50) MAPTALDH1A1L3MBTL1CYP1A2CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115348985-A Method for adjusting the electron energy level of a covalent organic framework for the manufacture of high-rate sodium-ion battery anodes 印度科学教育研究院 2022-11-15 CN claimed
CN-100543007-C Tetramine compound and organic EL HODOGAYA CHEMICAL CO LTD (JP) 2009-09-23 CN claimed
CN-1898191-A Tetramine compound and organic EL element HODOGAYA CHEMICAL CO LTD (JP) 2007-01-17 CN claimed
JP-8099941-A None JP disclosed
US-12091612-B2 Electrochromic element RICOH COMPANY, LTD. (JP) 2024-09-17 US disclosed
CN-111484478-B Preparation method and application of linear C2 symmetrical compound and lanthanide polynuclear complex thereof 中国科学院福建物质结构研究所 2022-12-06 CN disclosed
CN-115348985-A Method for adjusting the electron energy level of a covalent organic framework for the manufacture of high-rate sodium-ion battery anodes 印度科学教育研究院 2022-11-15 CN disclosed
CN-113929646-A Organic compound and organic electroluminescent device 北京鼎材科技有限公司 2022-01-14 CN disclosed
CN-113929585-A Organic compound and organic electroluminescent device 北京鼎材科技有限公司 2022-01-14 CN disclosed
EP-3889130-A1 ELECTROCHROMIC ELEMENT Ricoh Company, Ltd. (JP) 2021-10-06 EP disclosed
CN-113467146-A Electrochromic element 株式会社理光 2021-10-01 CN disclosed
CN-100543007-C Tetramine compound and organic EL HODOGAYA CHEMICAL CO LTD (JP) 2009-09-23 CN disclosed
CN-1898191-A Tetramine compound and organic EL element HODOGAYA CHEMICAL CO LTD (JP) 2007-01-17 CN disclosed
JP-2001181240-A METHOD FOR PRODUCING BENZIDINE COMPOUND HODOGAYA CHEM CO LTD 2001-07-03 JP disclosed
EP-0650955-B1 Amine compound and electro-luminescence device comprising same HODOGAYA CHEMICAL CO LTD (JP) 1998-08-19 EP disclosed
US-5707747-A CHARGE TRANSPORT COMPOUNDS HODOGAYA CHEMICAL CO., LTD. (JP) 1998-01-13 US disclosed
US-5639914-A DURABLE, STABLE, LOW VOLTAGE ELECTROLUMINESCENT EMITTERS HODOGAYA CHEMICAL CO., LTD. (JP) 1997-06-17 US disclosed
US-5585212-A LAYER HAVING BLEND OF HIGHER AND LOWER MOLECULAR WEIGHT POLYCARBONATES WITH CHARGE GENERATING AND CHARGE TRANSPORTING MATERIALS, SENSITIVITY, DURABILITY, STRENGTH, EASE OF MANUFACTURE MINOLTA CO., LTD. (JP) 1996-12-17 US disclosed
JP-H0899941-A AMINE COMPOUND HODOGAYA CHEM CO LTD 1996-04-16 JP disclosed
EP-0650955-A1 Amine compound and electro-luminescence device comprising same HODOGAYA CHEMICAL CO., LTD. (JP) 1995-05-03 EP disclosed