SCHEMBL9861779

SCHEMBL9861779

N#CCCCOS(=O)(O)=S

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.35
TDP1 Q9NUW8 1/20 0.35
NLRP3 Q96P20 1/20 0.33
TSHR P16473 2/20 0.32
CA1 P00915 7/20 0.31
CA2 P00918 7/20 0.31
CA9 Q16790 7/20 0.31
KDM4E B2RXH2 1/20 0.31
USP2 O75604 1/20 0.31
LMNA P02545 1/20 0.31
MMP9 P14780 1/20 0.31
ALOX15 P16050 1/20 0.31
CA12 O43570 2/20 0.30
CA3 P07451 2/20 0.30
CA4 P22748 2/20 0.30
CA6 P23280 2/20 0.30
CA5A P35218 2/20 0.30
CA7 P43166 2/20 0.30
CA14 Q9ULX7 2/20 0.30
CA5B Q9Y2D0 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9861342 0.94 CA1 (0.34) ALDH1A1TDP1NLRP3TSHRCA1
SCHEMBL9861358 0.92 CA1 (0.37) ALDH1A1TDP1NLRP3TSHRCA1
SCHEMBL2385734 0.86
SCHEMBL17469832 0.84 FNTA (0.37) ALDH1A1TDP1NLRP3TSHRCA1
Water SCHEMBL28188174 0.79 CA1 (0.48) ALDH1A1TSHRCA1CA2CA9
Water SCHEMBL4798302 0.79 CA1 (0.48) ALDH1A1TSHRCA1CA2CA9
SCHEMBL2035299 0.76 CA1 (0.50) ALDH1A1TSHRCA1CA2CA9
SCHEMBL9500520 0.76 TSHR (0.61) ALDH1A1TDP1NLRP3TSHRCA1
SCHEMBL18176767 0.74 TSHR (0.42) ALDH1A1NLRP3TSHRCA1CA2
Ammonia Solution, Strong SCHEMBL10892524 0.74 CA1 (0.48) ALDH1A1TSHRCA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0150168-B1 USE OF METAL SALTS OF THIOSULPHURIC -S-ESTERS AS RUBBER/METAL BONDING PROMOTERS MONSANTO EUROPE S.A./N.V. (BE) 1991-05-08 EP disclosed
US-4581297-A STEEL BELTED RADIAL TIRES MONSANTO EUROPE, S.A. (BE) 1986-04-08 US disclosed
EP-0150168-A2 Use of metal salts of thiosulphuric -S-esters as rubber/metal bonding promoters MONSANTO EUROPE S.A./N.V. (BE) 1985-07-31 EP disclosed