SCHEMBL9500520

SCHEMBL9500520

CS(=O)(=O)OCCCC#N

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.61
USP2 O75604 2/20 0.61
ALDH1A1 P00352 2/20 0.61
KDM4E B2RXH2 1/20 0.61
LMNA P02545 1/20 0.61
MMP9 P14780 1/20 0.61
ALOX15 P16050 1/20 0.61
NLRP3 Q96P20 1/20 0.44
CA1 P00915 14/20 0.32
CA2 P00918 14/20 0.32
CA9 Q16790 13/20 0.32
CA12 O43570 3/20 0.31
CA3 P07451 3/20 0.31
CA4 P22748 3/20 0.31
CA6 P23280 3/20 0.31
CA5A P35218 3/20 0.31
CA7 P43166 3/20 0.31
CA14 Q9ULX7 3/20 0.31
CA5B Q9Y2D0 3/20 0.31
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11399444 0.91 TSHR (0.62) TSHRUSP2ALDH1A1KDM4ELMNA
SCHEMBL13039363 0.86
SCHEMBL25352060 0.84 KDM4E (0.58) TSHRUSP2ALDH1A1KDM4ELMNA
SCHEMBL18176767 0.80 TSHR (0.42) TSHRUSP2ALDH1A1KDM4ELMNA
Busulfan SCHEMBL7195165 0.80 TSHR (0.94) TSHRUSP2ALDH1A1KDM4ELMNA
SCHEMBL11505252 0.78 NLRP3 (0.37) TSHRUSP2ALDH1A1KDM4ELMNA
SCHEMBL17469832 0.77 FNTA (0.37) TSHRUSP2ALDH1A1KDM4ELMNA
SCHEMBL313345 0.77 USP2 (0.61) TSHRUSP2ALDH1A1KDM4ELMNA
Busulfan SCHEMBL4373 0.77 TSHR (1.00) TSHRUSP2ALDH1A1KDM4ELMNA
Busulfan SCHEMBL4764696 0.77 TSHR (1.00) TSHRUSP2ALDH1A1KDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170222277-A1 ELECTROLYTE SOLUTION, ELECTROCHEMICAL DEVICE, LITHIUM ION SECONDARY BATTERY, AND MODULE DAIKIN INDUSTRIES, LTD. (JP) 2017-08-03 US disclosed
US-20160315354-A1 ELECTROLYTIC SOLUTION, ELECTROCHEMICAL DEVICE, LITHIUM-ION SECONDARY CELL, AND MODULE DAIKIN INDUSTRIES, LTD. (JP) 2016-10-27 US disclosed
US-5179212-A PROCESS FOR THE PREPARATION OF 3-PYRROLIDINOLS AND INTERMEDIATES THEREFOR KANEGAFUCHI CHEMICAL INDUSTRY CO., LTD. (JP) 1993-01-12 US disclosed