SCHEMBL9861801

SCHEMBL9861801

Cc1cc(NC(=O)c2ccccc2)c(C)cc1N

nearest known ligand 0.68

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.68
CYP1A2 P05177 1/20 0.68
CYP2C9 P11712 1/20 0.68
CYP2C19 P33261 1/20 0.68
HDAC2 Q92769 9/20 0.60
HDAC1 Q13547 5/20 0.60
HDAC3 O15379 3/20 0.60
POLB P06746 2/20 0.60
MAPK1 P28482 1/20 0.60
HPGD P15428 1/20 0.60
HDAC8 Q9BY41 1/20 0.57
HDAC6 Q9UBN7 1/20 0.57
KMT2A Q03164 3/20 0.55
MEN1 O00255 2/20 0.55
KCNMA1 Q12791 1/20 0.53
NCOR2 Q9Y618 1/20 0.50
PKM P14618 1/20 0.50
GRIK1 P39086 1/20 0.50
TDP1 Q9NUW8 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8777716 0.94 MAPT (0.68) MAPTCYP1A2CYP2C9CYP2C19HDAC2
SCHEMBL11592390 0.93 KMT2A (0.61) MAPTCYP1A2CYP2C9CYP2C19HDAC2
SCHEMBL14900902 0.90 POLB (0.72) MAPTCYP1A2CYP2C9CYP2C19HDAC2
SCHEMBL3445622 0.86 MAPT (0.62) MAPTCYP1A2CYP2C9CYP2C19HDAC2
SCHEMBL11314855 0.86 MAPT (0.62) MAPTCYP1A2CYP2C9CYP2C19HDAC2
SCHEMBL6491203 0.84 HDAC1 (0.63) MAPTCYP1A2CYP2C9CYP2C19HDAC2
SCHEMBL5475142 0.84 MEN1 (0.66) MAPTCYP1A2CYP2C9CYP2C19HDAC2
SCHEMBL131762 0.84 MEN1 (0.62) MAPTCYP1A2CYP2C9CYP2C19HDAC2
SCHEMBL29407250 0.84 MEN1 (0.62) MAPTCYP1A2CYP2C9CYP2C19HDAC2
SCHEMBL11575813 0.83 MAPT (0.62) MAPTCYP1A2CYP2C9CYP2C19HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8637437-B2 Lubricating composition containing a polymer THE LUBRIZOL CORPORATION (US) 2014-01-28 US disclosed
US-8354362-B2 Polymer and lubricating compositions thereof THE LUBRIZOL CORPORATION (US) 2013-01-15 US disclosed
US-20100298185-A1 Lubricating Composition Containing a Polymer THE LUBRIZOL CORPORATION (US) 2010-11-25 US disclosed
US-20100152082-A1 Polymer and Lubricating Compositions Thereof THE LUBRIZOL CORPORATION (US) 2010-06-17 US disclosed
US-5026831-A Water-insoluble disazo colorants having hetero-bicyclic methylene-active compounds as coupling component HOECHST AKTIENGESELLSCHAFT (DE) 1991-06-25 US disclosed
US-4263205-A FOR COLORING POLYMERS, LACQUERS CIBA-GEIGY CORPORATION (US) 1981-04-21 US disclosed
US-4220586-A FASTNESS TO LIGHT, OVER-LACQUERING, MIGRATION, WEATHERING, AND HEAT CIBA-GEIGY CORPORATION (US) 1980-09-02 US disclosed
US-4062838-A LACQUERS, PRINTING INKS, YELLOW TO ORANGE CIBA-GEIGY CORPORATION (US) 1977-12-13 US disclosed