Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | CA12 | O43570 | 2/20 | 0.55 |
| ▸ | CA1 | P00915 | 2/20 | 0.55 |
| ▸ | CA2 | P00918 | 2/20 | 0.55 |
| ▸ | CA7 | P43166 | 2/20 | 0.55 |
| ▸ | CA9 | Q16790 | 2/20 | 0.55 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | CA4 | P22748 | 1/20 | 0.55 |
| ▸ | CA6 | P23280 | 1/20 | 0.55 |
| ▸ | TPMT | P51580 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29587530 | 1.00 | KMT2A (0.64) | KMT2ATDP1CA12CA1CA2 | |
| SCHEMBL23605755 | 0.85 | TDP1 (0.54) | KMT2ATDP1LMNAGAACYP1A2 | |
| SCHEMBL28738503 | 0.82 | KMT2A (0.54) | KMT2ATDP1TPMTGAACYP1A2 | |
| 1,2,4-Trimethoxybenzene SCHEMBL27707740 | 0.82 | CA12 (0.64) | KMT2ACA12CA1CA2CA7 | |
| SCHEMBL10949249 | 0.82 | TDP1 (0.51) | KMT2ATDP1LMNAGAACYP1A2 | |
| Lactisole SCHEMBL10667608 | 0.81 | GAA (0.67) | KMT2ATDP1CA1CA2GAA | |
| Lactisole SCHEMBL5600662 | 0.81 | GAA (0.67) | KMT2ATDP1CA1CA2GAA | |
| Lactisole SCHEMBL352607 | 0.81 | GAA (0.67) | KMT2ATDP1CA1CA2GAA | |
| SCHEMBL4262556 | 0.80 | CYP1A2 (0.77) | KMT2ATDP1GAACYP1A2CYP2C9 | |
| SCHEMBL28561805 | 0.80 | LMNA (0.53) | KMT2ACA12CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114516792-B | 2- (3, 4, 5-trimethoxy phenoxy) propionic acid and preparation method and application thereof | 华南理工大学 | 2023-01-06 | — | — | CN | disclosed |
| CN-114516792-A | 2- (3,4, 5-trimethoxy phenoxy) propionic acid and preparation method and application thereof | 华南理工大学 | 2022-05-20 | — | — | CN | disclosed |
| CN-112876354-B | 2- (4-methoxyphenoxy) propionic acid derivative with sweet taste inhibiting effect and industrial production method thereof | 华南理工大学 | 2022-04-22 | — | — | CN | disclosed |
| CN-112876354-A | 2- (4-methoxyphenoxy) propionic acid derivative with sweet taste inhibiting effect and industrial production method thereof | 华南理工大学 | 2021-06-01 | — | — | CN | disclosed |
| US-5045336-A | Reducing sweet taste of high sugar foods, organic acids and acid salts | AMSTAR SUGAR CORPORATION (US) | 1991-09-03 | — | — | US | disclosed |
| EP-0159864-B1 | METHOD OF MODIFYING TASTE | TATE & LYLE PUBLIC LIMITED COMPANY (GB) | 1989-07-19 | — | — | EP | disclosed |
| US-4656189-A | INSECTICIDES | CORNELL RESEARCH FOUNDATION, INC. (US) | 1987-04-07 | — | — | US | disclosed |
| US-3935193-A | ANTIBIOTICS | TOYO JOZO KABUSHIKI KAISHA (JA) | 1976-01-27 | — | — | US | disclosed |