Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9057385 | 1.00 | MAPT (0.30) | MAPTCYP2D6CYP2C19ALDH1A1CYP3A4 | |
| SCHEMBL7746263 | 0.81 | MAPT (0.34) | MAPTCYP2D6CYP2C19 | |
| SCHEMBL7746260 | 0.81 | MAPT (0.34) | MAPTCYP2D6CYP2C19 | |
| SCHEMBL3935911 | 0.80 | CYP2D6 (0.38) | MAPTCYP2D6CYP2C19ALDH1A1CYP3A4 | |
| SCHEMBL3272672 | 0.80 | CYP2D6 (0.38) | MAPTCYP2D6CYP2C19ALDH1A1CYP3A4 | |
| SCHEMBL630861 | 0.76 | GRIK1 (0.41) | ALDH1A1 | |
| SCHEMBL3232685 | 0.76 | GRIK1 (0.41) | ALDH1A1 | |
| SCHEMBL2047661 | 0.76 | TDP1 (0.32) | — | |
| SCHEMBL11762637 | 0.74 | GABRP (0.33) | — | |
| SCHEMBL445565 | 0.74 | TDP1 (0.31) | MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4981913-A | SHELF LIFE, PAPERMAKING | BASF AKTIENGESELLSCHAFT (DE) | 1991-01-01 | — | — | US | disclosed |
| EP-0364798-A2 | Cross-linked, water soluble copolymers, process for their manufacture and use thereof | BASF Aktiengesellschaft (DE) | 1990-04-25 | — | — | EP | disclosed |