SCHEMBL9862833

SCHEMBL9862833

Cc1cc(CCCCCOc2ccc(-c3ncco3)cc2Br)on1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCHE P06276 1/20 0.36
ACHE P22303 1/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
CYP1A2 P05177 2/20 0.36
CYP2C19 P33261 2/20 0.36
CYP19A1 P11511 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2D6 P10635 2/20 0.35
NR1I2 O75469 1/20 0.35
CYP3A4 P08684 1/20 0.35
SCARB1 Q8WTV0 1/20 0.34
S1PR1 P21453 6/20 0.33
ALDH1A1 P00352 1/20 0.33
IGF1R P08069 2/20 0.33
FGFR1 P11362 2/20 0.33
KDR P35968 2/20 0.33
TTK P33981 1/20 0.32
S1PR3 Q99500 2/20 0.32
PRKAG1 P54619 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9862870 0.85 CYP19A1 (0.48) MEN1KMT2ACYP1A2CYP2C19CYP19A1
SCHEMBL9862922 0.85 CYP19A1 (0.48) MEN1KMT2ACYP1A2CYP2C19CYP19A1
SCHEMBL9863182 0.78 SCARB1 (0.36) BCHEACHEMEN1KMT2ACYP1A2
SCHEMBL9863055 0.78 SCARB1 (0.36) BCHEACHEMEN1KMT2ACYP1A2
SCHEMBL9705774 0.78 NR1I2 (0.41) MEN1KMT2ACYP1A2CYP2C19CYP19A1
SCHEMBL10507565 0.72 NR1I2 (0.40) MEN1KMT2ACYP1A2CYP2C19CYP19A1
SCHEMBL9863184 0.72 NR1I2 (0.41) BCHEACHEMEN1KMT2ACYP1A2
SCHEMBL8117789 0.71 PTPN1 (0.46) S1PR1ALDH1A1S1PR3
SCHEMBL9863113 0.71 CYP19A1 (0.48) BCHEACHEMEN1KMT2ACYP1A2
SCHEMBL9863021 0.71 CYP19A1 (0.48) BCHEACHEMEN1KMT2ACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5002960-A Viricides for combating picornaviruses STERLING DRUG, INC. (US) 1991-03-26 US disclosed
US-4939267-A Viricides STERLING DRUG INC. (US) 1990-07-03 US disclosed
US-4843087-A OXAZOLINYL COMPOUNDS; RHINOVIRUSES AND PICORNAVIRUSES STERLING DRUG INC. (US) 1989-06-27 US disclosed