SCHEMBL9863113

SCHEMBL9863113

Cc1cc(CCCCCOc2ccc(-c3nc(C)co3)cc2)on1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 3/20 0.48
CYP2C9 P11712 2/20 0.48
CYP2C19 P33261 2/20 0.48
CYP1A2 P05177 1/20 0.48
AOC3 Q16853 4/20 0.46
NR1I2 O75469 1/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2D6 P10635 1/20 0.40
HRH3 Q9Y5N1 1/20 0.38
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
S1PR1 P21453 1/20 0.37
S1PR3 Q99500 1/20 0.37
MAPT P10636 5/20 0.37
NPC1 O15118 5/20 0.37
RAB9A P51151 5/20 0.37
SMN1; SMN2 Q16637 4/20 0.37
HTT P42858 1/20 0.37
ALDH1A1 P00352 4/20 0.36
KDM4E B2RXH2 3/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9863021 1.00 CYP19A1 (0.48) CYP19A1CYP2C9CYP2C19CYP1A2AOC3
SCHEMBL9862922 0.86 CYP19A1 (0.48) CYP19A1CYP2C9CYP2C19CYP1A2NR1I2
SCHEMBL9862870 0.86 CYP19A1 (0.48) CYP19A1CYP2C9CYP2C19CYP1A2NR1I2
SCHEMBL9862976 0.84 CYP1A2 (0.46) CYP19A1CYP2C9CYP2C19CYP1A2NR1I2
SCHEMBL9208154 0.84 RAB9A (0.49) CYP19A1CYP2C9CYP2C19CYP1A2MEN1
SCHEMBL9204123 0.83 CYP19A1 (0.48) CYP19A1CYP2C9CYP2C19CYP1A2NR1I2
SCHEMBL9862972 0.82 CYP19A1 (0.47) CYP19A1CYP2C9CYP2C19CYP1A2NR1I2
SCHEMBL9205839 0.82 CYP2C9 (0.47) CYP19A1CYP2C9CYP2C19CYP1A2AOC3
SCHEMBL9862929 0.81 CYP19A1 (0.45) CYP19A1CYP2C9CYP2C19CYP1A2NR1I2
SCHEMBL9436495 0.80 CHRNB4 (0.53) AOC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-55056184-A None JP disclosed
US-5002960-A Viricides for combating picornaviruses STERLING DRUG, INC. (US) 1991-03-26 US disclosed
US-4990657-A From an aromatic halide without a phase transfer agent RHONE-POULENC CHIMIE (FR) 1991-02-05 US disclosed
US-4939267-A Viricides STERLING DRUG INC. (US) 1990-07-03 US disclosed
US-4843087-A OXAZOLINYL COMPOUNDS; RHINOVIRUSES AND PICORNAVIRUSES STERLING DRUG INC. (US) 1989-06-27 US disclosed
US-4536344-A USING A PHOSPINE OR PHOSPHITE BAYER AKTIENGESELLSCHAFT (DE) 1985-08-20 US disclosed
JP-S5556184-A AGENT FOR PREVENTING DISCOLORATION OF ORGANIC ISOCYANATE ASAHI CHEM IND CO LTD 1980-04-24 JP disclosed