Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | GRN | P28799 | 1/20 | 0.42 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9023287 | 0.86 | CYP3A4 (0.51) | CYP3A4KMT2AMEN1CYP19A1MAPT | |
| SCHEMBL9388155 | 0.85 | MAPT (0.44) | CYP3A4KMT2AMEN1CYP19A1MAPT | |
| SCHEMBL9823725 | 0.85 | CYP3A4 (0.53) | CYP3A4KMT2AMEN1CYP19A1MAPT | |
| SCHEMBL11182063 | 0.83 | CYP3A4 (0.50) | CYP3A4KMT2AMEN1CYP19A1MAPT | |
| SCHEMBL11075842 | 0.82 | CYP3A4 (0.49) | CYP3A4KMT2AMEN1CYP19A1MAPT | |
| SCHEMBL11075839 | 0.82 | CYP3A4 (0.49) | CYP3A4KMT2AMEN1CYP19A1MAPT | |
| SCHEMBL9823684 | 0.81 | CYP3A4 (0.41) | CYP3A4KMT2AMEN1MAPTTDP1 | |
| SCHEMBL9367760 | 0.80 | MEN1 (0.49) | CYP3A4KMT2AMEN1CYP19A1MAPT | |
| SCHEMBL5364455 | 0.76 | MAPT (0.77) | CYP3A4KMT2AMEN1CYP19A1MAPT | |
| SCHEMBL10362204 | 0.76 | MAPT (0.61) | CYP3A4KMT2AMEN1CYP19A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5011850-A | Substituted diazolylalkyl-carbinols, a process for their preparation and their use as antimycotic agents | BAYER AKTIENGESELLSCHAFT (DE) | 1991-04-30 | — | — | US | disclosed |
| EP-0131845-B1 | USE OF SUBSTITUTED DIAZOLYLALKYLCARBINOLS IN PLANT PROTECTION FOR THE CONTROL OF FUNGI | BAYER AG (DE) | 1987-09-02 | — | — | EP | disclosed |
| EP-0120276-B1 | SUBSTITUTED DIAZOLYLALKYL OR TRIAZOLYLALKYL CARBINOLS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS ANTIMYCOTIC COMPOUNDS | BAYER AG (DE) | 1986-10-15 | — | — | EP | disclosed |
| EP-0131845-A2 | Use of substituted diazolylalkylcarbinols in plant protection for the control of fungi | BAYER AG (DE) | 1985-01-23 | — | — | EP | disclosed |