Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.61 |
| ▸ | LTA4H | P09960 | 1/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.49 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.49 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.41 |
| ▸ | SCARB1 | Q8WTV0 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8539893 | 1.00 | HRH3 (0.61) | HRH3KCNH2LTA4HHDAC3HDAC4 | |
| SCHEMBL9668080 | 0.93 | HRH3 (0.68) | HRH3KCNH2LTA4HHDAC3HDAC4 | |
| SCHEMBL9217206 | 0.86 | KCNH2 (0.61) | HRH3KCNH2LTA4HHDAC3HDAC4 | |
| SCHEMBL9668251 | 0.86 | HRH3 (0.61) | HRH3KCNH2LTA4HHDAC3HDAC4 | |
| SCHEMBL31282734 | 0.86 | KCNH2 (0.61) | HRH3KCNH2LTA4HHDAC3HDAC4 | |
| SCHEMBL9213571 | 0.84 | HRH3 (0.65) | HRH3KCNH2LTA4HHDAC3HDAC4 | |
| SCHEMBL9219724 | 0.82 | HRH3 (0.57) | HRH3KCNH2LTA4HHDAC3HDAC4 | |
| SCHEMBL7448226 | 0.82 | KCNH2 (0.63) | HRH3KCNH2LTA4HHDAC3HDAC4 | |
| SCHEMBL10556017 | 0.78 | KCNH2 (0.53) | HRH3KCNH2LTA4HHDAC3HDAC4 | |
| SCHEMBL10556935 | 0.78 | KCNH2 (0.53) | HRH3KCNH2LTA4HHDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5002960-A | Viricides for combating picornaviruses | STERLING DRUG, INC. (US) | 1991-03-26 | — | — | US | disclosed |
| US-4939267-A | Viricides | STERLING DRUG INC. (US) | 1990-07-03 | — | — | US | disclosed |
| US-4843087-A | OXAZOLINYL COMPOUNDS; RHINOVIRUSES AND PICORNAVIRUSES | STERLING DRUG INC. (US) | 1989-06-27 | — | — | US | disclosed |