Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.63 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.63 |
| ▸ | LTA4H | P09960 | 1/20 | 0.61 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.47 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9668080 | 0.89 | HRH3 (0.68) | KCNH2HRH3LTA4HHDAC3HDAC4 | |
| SCHEMBL9213571 | 0.86 | HRH3 (0.65) | KCNH2HRH3LTA4HHDAC3HDAC4 | |
| SCHEMBL31282734 | 0.82 | KCNH2 (0.61) | KCNH2HRH3LTA4HHDAC3HDAC4 | |
| SCHEMBL9217206 | 0.82 | KCNH2 (0.61) | KCNH2HRH3LTA4HHDAC3HDAC4 | |
| SCHEMBL7459026 | 0.82 | KCNH2 (0.45) | KCNH2HRH3LTA4HHDAC3HDAC4 | |
| SCHEMBL8539893 | 0.82 | HRH3 (0.61) | KCNH2HRH3LTA4HHDAC3HDAC4 | |
| SCHEMBL9862868 | 0.82 | HRH3 (0.61) | KCNH2HRH3LTA4HHDAC3HDAC4 | |
| SCHEMBL9668251 | 0.82 | HRH3 (0.61) | KCNH2HRH3LTA4HHDAC3HDAC4 | |
| SCHEMBL11782167 | 0.79 | LTA4H (0.62) | KCNH2HRH3LTA4HACKR3 | |
| SCHEMBL9219724 | 0.79 | HRH3 (0.57) | KCNH2HRH3LTA4HHDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6433116-B1 | — | — | None | — | — | US | disclosed |
| US-6433116-B2 | CROSSLINKING; COATINGS, INKS, VARNISHES, SURFACE TREATMENT | S. C. JOHNSON COMMERCIAL MARKETS, INC. | 2002-08-13 | — | — | US | disclosed |
| US-20010018516-A1 | Oxazoline or oxazine acetoacetate aqueous coating compositions | BASF CORPORATION | 2001-08-30 | — | — | US | disclosed |
| US-6235901-B1 | CAN BE POLYMERIZED AND/OR COPOLYMERIZED BY CATONIC POLYMERIZATION; CAN BE CROSSLINKED AND ARE USEFUL IN COATINGS, INKS, OVERPRINT VARNISHES, AND SURFACE TREATMENT APPLICATIONS. | S. C. JOHNSON COMMERCIAL MARKETS, INC. | 2001-05-22 | — | — | US | disclosed |
| WO-2000068212-A1 | OXAZOLINE OR OXAZINE ACETOACETATE AQUEOUS COATING COMPOSITIONS | S. C. JOHNSON COMMERCIAL MARKETS, INC. (US) | 2000-11-16 | — | — | WO | disclosed |
| US-6063885-A | Oxazoline or oxazine methacrylate aqueous coating compositions | S. C. JOHNSON COMMERCIAL MARKETS, INC. (US) | 2000-05-16 | — | — | US | disclosed |
| EP-0472560-B1 | CYCLIC POLYIMINOETHERS | HENKEL KGAA (DE) | 1996-07-10 | — | — | EP | disclosed |
| WO-1996016999-A1 | OXAZOLINE-TERMINATED POLYURETHANES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1996-06-06 | — | — | WO | disclosed |
| US-5196544-A | CYCLIC OLIGOIMINOETHERS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1993-03-23 | — | — | US | disclosed |
| EP-0472560-A1 | NEW CYCLIC POLYIMINOETHERS. | HENKEL KGAA (DE) | 1992-03-04 | — | — | EP | disclosed |
| WO-1990014341-A1 | NEW CYCLIC POLYIMINOETHERS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1990-11-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010018516-A1 | Oxazoline or oxazine acetoacetate aqueous coating compositions | ITGB7, DNMT3A, KAT7 | KCNH2 584/4885HRH3 249/4885LTA4H 2133/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.