Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7428193 | 0.76 | PARP10 (0.50) | PARP10ALDH1A1TDP1RECQLKCNA3 | |
| SCHEMBL9556813 | 0.76 | PARP10 (0.51) | PARP10TDP1KCNA3L3MBTL1PPARA | |
| SCHEMBL9556809 | 0.76 | PARP10 (0.51) | PARP10TDP1KCNA3L3MBTL1PPARA | |
| SCHEMBL9860147 | 0.75 | PARP10 (0.53) | PARP10ALDH1A1TDP1RECQLKCNA3 | |
| SCHEMBL5523873 | 0.74 | TDP1 (0.70) | PARP10ALDH1A1TDP1RECQLKCNA3 | |
| SCHEMBL14681222 | 0.74 | GRIK1 (0.64) | — | |
| SCHEMBL5288095 | 0.73 | TDP1 (0.55) | PARP10ALDH1A1TDP1KCNA3PKM | |
| SCHEMBL5515375 | 0.73 | TDP1 (0.59) | PARP10TDP1RECQLKCNA3L3MBTL1 | |
| SCHEMBL353031 | 0.72 | PARP10 (0.53) | PARP10ALDH1A1TDP1GAAPKM | |
| SCHEMBL1326062 | 0.72 | PARP10 (0.61) | PARP10ALDH1A1TDP1RECQLKCNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4988828-A | Antiulcer agents, antagonist for histamine H2 receptors | FUJIREBIO KABUSHIKI KAISHA (JP) | 1991-01-29 | — | — | US | disclosed |
| EP-0318036-A2 | Phenoxypropyl derivatives | FUJIREBIO KABUSHIKI KAISHA (JP) | 1989-05-31 | — | — | EP | disclosed |