Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.46 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | HRH2 | P25021 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9556809 | 1.00 | PARP10 (0.51) | PARP10MAPTL3MBTL1CTNNB1KCNA3 | |
| SCHEMBL7353938 | 0.90 | CTNNB1 (0.48) | PARP10MAPTL3MBTL1CTNNB1KCNA3 | |
| SCHEMBL9556717 | 0.90 | CTNNB1 (0.48) | PARP10MAPTL3MBTL1CTNNB1KCNA3 | |
| SCHEMBL8900559 | 0.81 | MTNR1A (0.57) | PARP10MAPTL3MBTL1CTNNB1MTNR1A | |
| SCHEMBL30444684 | 0.78 | CTNNB1 (0.43) | L3MBTL1CTNNB1MTNR1AMEN1KMT2A | |
| SCHEMBL10420797 | 0.76 | CTNNB1 (0.44) | PARP10CTNNB1KCNA3FFAR1AKR1B1 | |
| SCHEMBL5697803 | 0.76 | CTNNB1 (0.51) | PARP10L3MBTL1CTNNB1MTNR1AMEN1 | |
| SCHEMBL9862877 | 0.76 | PARP10 (0.53) | PARP10L3MBTL1KCNA3TDP1PPARA | |
| SCHEMBL7280245 | 0.73 | CTNNB1 (0.52) | CTNNB1KMT2ATDP1SLC1A3SLC1A2 | |
| SCHEMBL5707319 | 0.73 | MMP9 (0.52) | L3MBTL1CTNNB1MTNR1ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5258362-A | Enzyme inhibitors, amides with oxetane ring | ABBOTT LABORATORIES (US) | 1993-11-02 | — | — | US | disclosed |