Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | SCARB1 | Q8WTV0 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | WDR5 | P61964 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | THRA | P10827 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9665936 | 0.81 | TDP1 (0.39) | KCNH2HRH3LTA4HSCARB1HPGD | |
| SCHEMBL9863111 | 0.80 | KCNH2 (0.35) | KCNH2HRH3LTA4HSCARB1KMT2A | |
| SCHEMBL9863109 | 0.80 | KCNH2 (0.35) | KCNH2HRH3LTA4HSCARB1KMT2A | |
| SCHEMBL9668088 | 0.80 | TDP1 (0.38) | KCNH2HRH3LTA4HSCARB1HPGD | |
| SCHEMBL9666735 | 0.80 | TDP1 (0.38) | KCNH2HRH3LTA4HSCARB1HPGD | |
| SCHEMBL9667163 | 0.80 | TDP1 (0.38) | KCNH2HRH3LTA4HSCARB1HPGD | |
| SCHEMBL9667744 | 0.80 | TDP1 (0.38) | KCNH2HRH3LTA4HSCARB1HPGD | |
| SCHEMBL9668251 | 0.79 | HRH3 (0.61) | KCNH2HRH3LTA4HHDAC3HDAC4 | |
| SCHEMBL9668279 | 0.78 | TDP1 (0.39) | KCNH2HRH3LTA4HSCARB1HPGD | |
| SCHEMBL9220079 | 0.78 | HPGD (0.40) | KCNH2HRH3LTA4HHPGDWDR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5002960-A | Viricides for combating picornaviruses | STERLING DRUG, INC. (US) | 1991-03-26 | — | — | US | disclosed |
| US-4939267-A | Viricides | STERLING DRUG INC. (US) | 1990-07-03 | — | — | US | disclosed |
| US-4843087-A | OXAZOLINYL COMPOUNDS; RHINOVIRUSES AND PICORNAVIRUSES | STERLING DRUG INC. (US) | 1989-06-27 | — | — | US | disclosed |