SCHEMBL9863226

SCHEMBL9863226

CCCCCCCCCC(=O)O[C@@H](C#N)c1cccc(Oc2ccccc2)c1

nearest known ligand 0.51

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.51
TDP1 Q9NUW8 1/20 0.51
PTGS1 P23219 1/20 0.45
MEN1 O00255 1/20 0.44
CYP2D6 P10635 1/20 0.44
KMT2A Q03164 1/20 0.44
CETP P11597 1/20 0.44
ALOX5 P09917 1/20 0.43
CYSLTR2 Q9NS75 3/20 0.43
CYSLTR1 Q9Y271 3/20 0.43
LMNA P02545 3/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
TLR2 O60603 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9863225 1.00 ALDH1A1 (0.51) ALDH1A1TDP1PTGS1MEN1CYP2D6
SCHEMBL27413143 0.95 ALDH1A1 (0.53) ALDH1A1TDP1PTGS1MEN1CYP2D6
SCHEMBL5161874 0.91 ALDH1A1 (0.54) ALDH1A1TDP1PTGS1MEN1CYP2D6
SCHEMBL5161879 0.91 ALDH1A1 (0.54) ALDH1A1TDP1PTGS1MEN1CYP2D6
SCHEMBL9863148 0.88 ALDH1A1 (0.55) ALDH1A1TDP1PTGS1MEN1CYP2D6
SCHEMBL9863147 0.88 ALDH1A1 (0.55) ALDH1A1TDP1PTGS1MEN1CYP2D6
SCHEMBL9863150 0.85 TDP1 (0.53) ALDH1A1TDP1PTGS1MEN1CYP2D6
SCHEMBL9863144 0.85 TDP1 (0.53) ALDH1A1TDP1PTGS1MEN1CYP2D6
SCHEMBL11045825 0.81 ALDH1A1 (0.54) ALDH1A1TDP1PTGS1MEN1CYP2D6
SCHEMBL9862890 0.81 ALDH1A1 (0.53) ALDH1A1TDP1PTGS1MEN1CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4985365-A WITH AN ESTERASE FROM A MICROORGANISM, ASSYMETRIC HYDROLYSIS SUMITOMO CHEMICAL COMPANY, LTD. (JP) 1991-01-15 US disclosed
EP-0080827-B1 METHOD FOR BIOTECHNOLOGICALLY PREPARING (S)-(-)-ALPHA-CYANO-3-PHENOXYBENZYL ALCOHOL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1988-03-09 EP disclosed
EP-0080827-A2 Method for biotechnologically preparing (S)-(-)-alpha-cyano-3-phenoxybenzyl alcohol SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1983-06-08 EP disclosed