SCHEMBL9863519

SCHEMBL9863519

CCCCCCCCCCCCCCCCCCNC(=O)OCC(COC(=O)NC(=O)C(C)CCN(C)C)OC

nearest known ligand 0.57

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
GMNN O75496 1/20 0.44
USP2 O75604 1/20 0.44
LMNA P02545 1/20 0.44
PTAFR P25105 1/20 0.44
MTOR P42345 1/20 0.44
BLM P54132 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9691792 0.85 EPHX1 (0.51)
SCHEMBL9863505 0.85 EPHX1 (0.51)
SCHEMBL9863506 0.82
SCHEMBL9863521 0.81 DNM1 (0.52)
SCHEMBL9863459 0.80
Hydrochloric Acid SCHEMBL9863422 0.79
SCHEMBL9863501 0.78
SCHEMBL9863401 0.77
Hydrochloric Acid SCHEMBL9863474 0.76
SCHEMBL9863810 0.76 EPHX1 (0.56)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5025005-A Preventive or therapeutic agents for circulatory diseases, allergic disorders; antineoplastic agent; inhibitor for platelet activating factor TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1991-06-18 US disclosed
US-4737518-A ANTIALLERGENS, ANTINEOPLASTICS, ANTICOAGULANTS, CIRCULATORY DISEASES TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1988-04-12 US disclosed
EP-0157609-A2 Lipid derivatives their production and use Takeda Chemical Industries, Ltd. (JP) 1985-10-09 EP disclosed