SCHEMBL986389

SCHEMBL986389

C=C(CCCC(Br)Br)C(=O)O

nearest known ligand 0.37

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TET2 Q6N021 4/20 0.37
TET3 O43151 1/20 0.37
TET1 Q8NFU7 1/20 0.37
GRIK1 P39086 1/20 0.35
GRIK2 Q13002 1/20 0.35
GRM1 Q13255 1/20 0.35
GRM2 Q14416 1/20 0.35
TBXAS1 P24557 2/20 0.35
ALOX15 P16050 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2772998 0.86 TET2 (0.39) TET2TET3TET1GRIK1GRIK2
SCHEMBL1401880 0.79 TET2 (0.43) TET2TET3TET1GRIK1GRIK2
SCHEMBL27627 0.77 BLM (0.42) TET2TET3TET1GRIK1GRIK2
SCHEMBL6063563 0.77 TET2 (0.37) TET2TET3TET1GRIK1GRIK2
SCHEMBL18047808 0.77 GRIK1 (0.45) TET2TET3TET1GRIK1GRIK2
SCHEMBL2025802 0.77 TBXAS1 (0.47) TET2TET3TET1GRIK1GRIK2
SCHEMBL7989948 0.77 SLC22A6 (0.44) TET2TET3TET1GRIK1GRIK2
SCHEMBL148011 0.76 TET2 (0.40) TET2TET3TET1GRIK1GRIK2
SCHEMBL3132933 0.76 TET2 (0.40) TET2TET3TET1GRIK1GRIK2
SCHEMBL7935296 0.76 GRIK1 (0.43) TET2TET3TET1GRIK1GRIK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3790507-A1 VISION CORRECTION WITH LASER REFRACTIVE INDEX CHANGES University of Rochester (US) 2021-03-17 EP disclosed
EP-3389560-A1 REFRACTIVE CORRECTOR INCORPORATING A CONTINUOUS CENTRAL PHASE ZONE AND PERIPHERAL PHASE DISCONTINUITIES The University of Rochester (US) 2018-10-24 EP disclosed
WO-2017106321-A1 REFRACTIVE CORRECTOR INCORPORATING A CONTINUOUS CENTRAL PHASE ZONE AND PERIPHERAL PHASE DISCONTINUITIES UNIVERSITY OF ROCHESTER (US) 2017-06-22 WO disclosed
US-9187578-B2 Polymer modified pigment and production process of the same DIC CORPORATION (JP) 2015-11-17 US disclosed
US-9018299-B2 Colored fluid and multi-phase liquid colored composition DIC CORPORATION (JP) 2015-04-28 US disclosed
US-20140374668-A1 COLORED FLUID AND MULTI-PHASE LIQUID COLORED COMPOSITION DIC CORPORATION (JP) 2014-12-25 US disclosed
US-8426499-B2 Offset printing ink DIC CORPORATION (JP) 2013-04-23 US disclosed
EP-1646024-B1 RETROREFLECTIVE SHEET FOR SECURITY AND METHOD FOR MANUFACTURING THE SAME KIWA CHEMICAL IND CO LTD (JP) 2012-11-07 EP disclosed
US-8268200-B2 Pigment dispersing composition for color filter DIC CORPORATION (JP) 2012-09-18 US disclosed
US-8003197-B2 Retroreflective sheet for security and method for manufacturing the same KIWA CHEMICAL INDUSTRY CO., LTD. (JP) 2011-08-23 US disclosed
US-20100267894-A1 POLYMER MODIFIED PIGMENT AND PRODUCTION PROCESS OF THE SAME DIC CORPORATION (JP) 2010-10-21 US disclosed
US-7709417-B2 Security sticker and method for manufacturing the same KIWA CHEMICAL INDUSTRY CO., LTD. (JP) 2010-05-04 US disclosed
US-7238644-B2 Laminate for printing and, printing method and printed matter using the same KIWA CHEMICAL INDUSTRY CO., LTD. (JP) 2007-07-03 US disclosed
US-20060211572-A1 Security sticker and process for producing the same KIWA CHEMICAL INDUSTRY CO., LTD. (JP) 2006-09-21 US disclosed
US-20060188700-A1 Retroreflective sheet for security and method for manufacturing the same KIWA CHEMICAL INDUSTRY CO., LTD. (JP) 2006-08-24 US disclosed
EP-1646023-A1 SECURITY STICKER AND PROCESS FOR PRODUCING THE SAME Kiwa Chemical Industry Co., Ltd. (JP) 2006-04-12 EP disclosed
EP-1646024-A1 RETROREFLECTION SHEET FOR SECURITY AND PROCESS FOR PRODUCING THE SAME Kiwa Chemical Industry Co., Ltd. (JP) 2006-04-12 EP disclosed
US-20050148469-A1 Laminate for printing and, printing method and printed matter using the same KIWA CHEMICAL INDUSTRY CO., LTD. (JP) 2005-07-07 US disclosed
EP-0073765-A1 RADIO-OPAQUE MATERIAL NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) 1983-03-16 EP disclosed
WO-1982001006-A1 RADIO-OPAQUE MATERIAL CAUSTON B 1982-04-01 WO disclosed