SCHEMBL9863994

SCHEMBL9863994

CC(O)COC(C)COCCOCCOCC1CCCO1

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.46
PRMT5 O14744 1/20 0.36
WDR77 Q9BQA1 1/20 0.36
LMNA P02545 1/20 0.35
POLB P06746 1/20 0.35
DRD2 P14416 1/20 0.34
HTR2A P28223 1/20 0.34
HRH1 P35367 1/20 0.34
ALDH1A1 P00352 1/20 0.34
PDK1 Q15118 2/20 0.33
HPGD P15428 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
TSHR P16473 1/20 0.31
HSD17B10 Q99714 1/20 0.31
KDM4E B2RXH2 1/20 0.30
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9876569 1.00 TDP1 (0.46) TDP1PRMT5WDR77LMNAPOLB
SCHEMBL9863593 0.99 TDP1 (0.45) TDP1PRMT5WDR77LMNAPOLB
SCHEMBL9863774 0.99 TDP1 (0.47) TDP1PRMT5WDR77LMNAPOLB
SCHEMBL9863576 0.97 TDP1 (0.46) TDP1PRMT5WDR77LMNAPOLB
SCHEMBL9863801 0.92 TDP1 (0.44) TDP1PRMT5WDR77LMNAPOLB
SCHEMBL9863674 0.90 TDP1 (0.42) TDP1PRMT5WDR77LMNAPOLB
SCHEMBL10781866 0.90 TDP1 (0.42) TDP1PRMT5WDR77LMNAPOLB
SCHEMBL9863870 0.90 TDP1 (0.42) TDP1PRMT5WDR77LMNAPOLB
SCHEMBL9864444 0.90 TDP1 (0.42) TDP1PRMT5WDR77LMNAPOLB
SCHEMBL9863698 0.90 LMNA (0.40) TDP1PRMT5WDR77LMNAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5015524-A Lens sheet MITSUBISHI RAYON COMPANY, LTD. (JP) 1991-05-14 US disclosed
EP-0376254-A2 Lens sheet MITSUBISHI RAYON CO., LTD. (JP) 1990-07-04 EP disclosed