Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.65 |
| ▸ | LMNA | P02545 | 3/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.65 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.65 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.61 |
| ▸ | RAD51 | Q06609 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | HTT | P42858 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | RAD1 | O60671 | 1/20 | 0.60 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.60 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.60 |
| ▸ | LGMN | Q99538 | 1/20 | 0.53 |
| ▸ | CNR2 | P34972 | 2/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | PHGDH | O43175 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8263576 | 0.85 | MAPT (0.62) | MAPTLMNASMN1; SMN2L3MBTL1RAD51 | |
| SCHEMBL30802787 | 0.83 | RAD51 (0.63) | MAPTLMNASMN1; SMN2ALOX12L3MBTL1 | |
| SCHEMBL13282564 | 0.83 | RAD51 (0.50) | MAPTLMNASMN1; SMN2ALOX12L3MBTL1 | |
| SCHEMBL13282557 | 0.83 | RAD51 (0.50) | MAPTLMNASMN1; SMN2ALOX12L3MBTL1 | |
| SCHEMBL2712193 | 0.83 | LGMN (0.62) | MAPTLMNASMN1; SMN2ALOX12L3MBTL1 | |
| SCHEMBL19406876 | 0.83 | MAPT (0.58) | MAPTLMNASMN1; SMN2ALOX12L3MBTL1 | |
| SCHEMBL10274764 | 0.83 | RAD51 (0.63) | MAPTLMNASMN1; SMN2ALOX12L3MBTL1 | |
| SCHEMBL15094133 | 0.83 | LGMN (0.49) | MAPTLMNASMN1; SMN2ALOX12L3MBTL1 | |
| SCHEMBL12814354 | 0.83 | RAD51 (0.49) | MAPTLMNASMN1; SMN2ALOX12L3MBTL1 | |
| SCHEMBL2087597 | 0.83 | LGMN (0.67) | MAPTLMNASMN1; SMN2ALOX12L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1024317-C | Antifungal agents based on amides containing phenyl group | RHONE POULENC AGROCHIMIE (FR) | 1994-04-27 | — | — | CN | disclosed |
| US-5047432-A | Antidepressants | THE BOOTS COMPANY PLC (GB) | 1991-09-10 | — | — | US | disclosed |