Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.96 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.96 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.96 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | NOS1 | P29475 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL909845 | 0.98 | HSD17B10 (1.00) | HSD17B10GABRA5GABRB2LMNANOS1 | |
| Hydrochloric Acid SCHEMBL9694699 | 0.96 | GABRA5 (0.96) | HSD17B10GABRA5GABRB2LMNANOS1 | |
| Methyl Alcohol SCHEMBL10946415 | 0.94 | HSD17B10 (0.93) | HSD17B10GABRA5GABRB2LMNANOS1 | |
| Acetic Acid SCHEMBL27742442 | 0.93 | HSD17B10 (0.89) | HSD17B10GABRA5GABRB2LMNANOS1 | |
| SCHEMBL28100058 | 0.83 | GABRA5 (0.71) | HSD17B10GABRA5GABRB2GAAALDH1A1 | |
| SCHEMBL7845357 | 0.83 | GABRA5 (0.71) | HSD17B10GABRA5GABRB2GAAALDH1A1 | |
| SCHEMBL1797901 | 0.82 | GABRA5 (0.72) | HSD17B10GABRA5GABRB2LMNANOS1 | |
| SCHEMBL17492250 | 0.81 | GABRA5 (0.70) | HSD17B10GABRA5GABRB2NOS1GAA | |
| SCHEMBL11926737 | 0.81 | HSD17B10 (0.70) | HSD17B10GABRA5GABRB2NOS1GAA | |
| SCHEMBL3736516 | 0.81 | GABRA5 (0.70) | HSD17B10GABRA5GABRB2NOS1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5011938-A | Antimicrobials | ELI LILLY AND COMPANY (US) | 1991-04-30 | — | — | US | disclosed |
| US-4940718-A | BACTERICIDES | ELI LILLY AND COMPANY (US) | 1990-07-10 | — | — | US | disclosed |