SCHEMBL9864456

SCHEMBL9864456

CCN(c1cccc(C)c1N)C(C)OC

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CD44 P16070 1/20 0.36
SCN4A P35499 7/20 0.33
LMNA P02545 2/20 0.33
SCN1A P35498 2/20 0.33
SCN5A Q14524 2/20 0.33
SCN9A Q15858 2/20 0.33
CYP1A2 P05177 2/20 0.33
CYP3A4 P08684 2/20 0.33
CYP2D6 P10635 2/20 0.33
NFKB1 P19838 2/20 0.33
MAOA P21397 2/20 0.33
CYP2C9 P11712 1/20 0.33
TSHR P16473 1/20 0.33
KCNK3 O14649 1/20 0.33
CACNA1F O60840 1/20 0.33
KCNK2 O95069 1/20 0.33
GBA1 P04062 1/20 0.33
HTR2A P28223 1/20 0.33
SLC6A4 P31645 1/20 0.33
HTR2B P41595 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10766412 0.83 CYP3A4 (0.37) LMNACYP3A4TSHRSLC6A4
SCHEMBL7733713 0.79 ESR1 (0.34) LMNAHTR2AKCNH2
SCHEMBL5708973 0.72 CD44 (0.46) CD44SCN4ALMNASCN5ASCN9A
SCHEMBL22710567 0.72 TP53 (0.42) CYP3A4TSHR
SCHEMBL22710566 0.72 TP53 (0.42) CYP3A4TSHR
SCHEMBL20289896 0.71 CD44 (0.45) CD44SCN4ALMNASCN5ASCN9A
SCHEMBL10061779 0.69 IGLV6-57 (0.38) LMNACRHR1
SCHEMBL5084506 0.69 S100B (0.56) CYP3A4TSHRCRHR1
SCHEMBL7512821 0.69 MEN1 (0.38) CD44LMNACRHR1
SCHEMBL11580018 0.68 TDP1 (0.48) LMNACYP1A2CYP3A4CYP2D6MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5011763-A Polysulfidediamine Bleach Accelerators FUJI PHOTO FILM CO., LTD. (JP) 1991-04-30 US disclosed
US-4727008-A MULTILAYER-IMAGEWISE EXPOSURE TO ELECTRICAL CHARGES OF DIFFERENT POLARITIES TO GIVE DEVELOPABLE IMAGES EASTMAN KODAK COMPANY (US) 1988-02-23 US disclosed