Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15828589 | 0.73 | ALDH1A1 (0.36) | SMN1; SMN2 | |
| SCHEMBL22746606 | 0.73 | — | — | |
| SCHEMBL9301611 | 0.71 | SMN1; SMN2 (0.94) | SMN1; SMN2CA1CA9 | |
| SCHEMBL20582013 | 0.71 | SMN1; SMN2 (0.94) | SMN1; SMN2CA1CA9 | |
| SCHEMBL30075317 | 0.71 | SMN1; SMN2 (0.94) | SMN1; SMN2CA1CA9 | |
| SCHEMBL23621134 | 0.71 | SMN1; SMN2 (0.94) | SMN1; SMN2CA1CA9 | |
| SCHEMBL22001696 | 0.71 | SMN1; SMN2 (0.94) | SMN1; SMN2CA1CA9 | |
| SCHEMBL804333 | 0.71 | SMN1; SMN2 (0.94) | SMN1; SMN2CA1CA9 | |
| SCHEMBL3821916 | 0.70 | SMN1; SMN2 (0.36) | SMN1; SMN2CA1CA9 | |
| SCHEMBL10717956 | 0.69 | SMN1; SMN2 (0.48) | SMN1; SMN2CA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4983766-A | Chemical intermediates for optically active secondary alcohols | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-01-08 | — | — | US | disclosed |
| US-4812476-A | SECONDARY ALCOHOLS FROM ALDEHYDE AND 3-HYDROXYBUTYRIC ACID | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-03-14 | — | — | US | disclosed |
| EP-0244143-A2 | Substituted dioxanones and dioxinones | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-11-04 | — | — | EP | disclosed |