Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 4/20 | 0.51 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 4/20 | 0.37 |
| ▸ | PPARD | Q03181 | 4/20 | 0.37 |
| ▸ | PPARA | Q07869 | 4/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.37 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.37 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.37 |
| ▸ | TLR2 | O60603 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL125028 | 0.88 | CA2 (0.48) | CA2TSHRTDP1CYP3A4ATM | |
| Succinic Acid SCHEMBL15841614 | 0.87 | CA2 (0.65) | CA2TSHRTDP1CYP3A4ATM | |
| SCHEMBL11702972 | 0.84 | CA2 (0.46) | CA2TSHRTDP1CYP3A4ATM | |
| SCHEMBL1526985 | 0.84 | CA2 (0.46) | CA2TSHRTDP1CYP3A4ATM | |
| Succinic Acid SCHEMBL27521723 | 0.82 | CA2 (0.46) | CA2TSHRTDP1CYP3A4ATM | |
| SCHEMBL11701591 | 0.81 | NR1I2 (0.45) | CA2TSHRTDP1CYP3A4ALDH1A1 | |
| Succinic Acid SCHEMBL10595742 | 0.80 | CA2 (0.47) | CA2TSHRTDP1CYP3A4ATM | |
| Sulfuric Acid SCHEMBL10343524 | 0.78 | CYP3A4 (0.66) | CA2TSHRTDP1CYP3A4ATM | |
| Sulfuric Acid SCHEMBL10598843 | 0.78 | CYP3A4 (0.66) | CA2TSHRTDP1CYP3A4ATM | |
| Succinic Acid SCHEMBL28641955 | 0.77 | CYP3A4 (0.49) | CA2TSHRTDP1CYP3A4ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118006701-A | Preparation method of phospholipid DHA | 南京工业大学 | 2024-05-10 | — | — | CN | disclosed |
| US-5051335-A | Multilayer element of silver halide emulsion on paper support, subbing layer with antifogging agent | FUJI PHOTO FILM CO., LTD. (JP) | 1991-09-24 | — | — | US | disclosed |
| US-4774162-A | POLYMERIC MORDANTS, MULTILAYERS | FUJI PHOTO FILM CO., LTD. (JP) | 1988-09-27 | — | — | US | disclosed |