Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | PGR | P06401 | 1/20 | 0.61 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | OGG1 | O15527 | 1/20 | 0.51 |
| ▸ | MMP2 | P08253 | 1/20 | 0.51 |
| ▸ | FABP3 | P05413 | 5/20 | 0.50 |
| ▸ | FABP7 | O15540 | 4/20 | 0.50 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL37865 | 0.83 | ALDH1A1 (0.65) | ALDH1A1HSD17B10GAAPGRPTGS1 | |
| SCHEMBL7181428 | 0.83 | ALDH1A1 (0.65) | ALDH1A1HSD17B10GAAPGRPTGS1 | |
| SCHEMBL29901836 | 0.83 | ALDH1A1 (0.65) | ALDH1A1HSD17B10GAAPGRPTGS1 | |
| SCHEMBL864919 | 0.82 | ALDH1A1 (0.62) | ALDH1A1HSD17B10GAAPGRPTGS1 | |
| SCHEMBL399266 | 0.82 | ALDH1A1 (0.62) | ALDH1A1HSD17B10GAAPGRPTGS1 | |
| SCHEMBL4949311 | 0.81 | ALDH1A1 (0.57) | ALDH1A1HSD17B10GAAPGRPTGS1 | |
| Alpha-Naphthylacetate SCHEMBL76633 | 0.80 | ALDH1A1 (0.66) | ALDH1A1HSD17B10GAAPGRPTGS1 | |
| SCHEMBL1395198 | 0.80 | ALDH1A1 (0.61) | ALDH1A1HSD17B10GAAPGRPTGS1 | |
| SCHEMBL11225475 | 0.80 | HSD17B10 (0.61) | ALDH1A1HSD17B10GAAPGRPTGS1 | |
| SCHEMBL1043115 | 0.80 | ALDH1A1 (0.61) | ALDH1A1HSD17B10GAAPGRPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5055125-A | Thiocarbamates with dithiocarbamic acid derivatives | NITROKEMIA IPARTELEPEK (HU) | 1991-10-08 | — | — | US | disclosed |
| US-5055125-A | Thiocarbamates with dithiocarbamic acid derivatives | NITROKEMIA IPARTELEPEK (HU) | 1991-10-08 | — | — | US | disclosed |