Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA4 | P48058 | 2/20 | 0.48 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.45 |
| ▸ | FNTA | P49354 | 14/20 | 0.39 |
| ▸ | FNTB | P49356 | 14/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9865583 | 0.82 | GRIA4 (0.48) | GRIA4FNTAFNTBALDH1A1KMT2A | |
| SCHEMBL9864594 | 0.81 | GRIA4 (0.47) | GRIA4GRIA2FNTAFNTBALDH1A1 | |
| SCHEMBL9865433 | 0.77 | GRIA4 (0.56) | GRIA4GRIA2FNTAFNTBALDH1A1 | |
| SCHEMBL5758052 | 0.74 | GRIA4 (0.64) | GRIA4GRIA2FNTAFNTBALDH1A1 | |
| SCHEMBL9866049 | 0.74 | GRIA4 (0.39) | GRIA4GRIA2FNTAFNTBALDH1A1 | |
| SCHEMBL5757897 | 0.73 | GRIA4 (0.40) | GRIA4GRIA2FNTAFNTBALDH1A1 | |
| SCHEMBL1551995 | 0.71 | GRIA4 (0.57) | GRIA4GRIA2FNTAFNTBALDH1A1 | |
| SCHEMBL6644214 | 0.71 | GRIA4 (0.47) | GRIA4GRIA2ALDH1A1MAPK1HTT | |
| SCHEMBL3818516 | 0.71 | GRIA4 (0.57) | GRIA4GRIA2FNTAFNTBALDH1A1 | |
| SCHEMBL1551473 | 0.70 | GRIA4 (0.46) | GRIA4GRIA2FNTAFNTBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4994485-A | Seed and soil fungi, bacteria | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1991-02-19 | — | — | US | disclosed |
| EP-0234622-B1 | NEW THIO COMPOUNDS HAVING FUNGICIDAL ACTIVITY | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1990-06-27 | — | — | EP | disclosed |
| EP-0234622-A1 | New thio compounds having fungicidal activity | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1987-09-02 | — | — | EP | disclosed |