Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA4 | P48058 | 2/20 | 0.39 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.36 |
| ▸ | CNKSR1 | Q969H4 | 1/20 | 0.34 |
| ▸ | CCNC | P24863 | 1/20 | 0.34 |
| ▸ | CDK8 | P49336 | 1/20 | 0.34 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | FNTA | P49354 | 1/20 | 0.30 |
| ▸ | FNTB | P49356 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9864884 | 0.79 | GRIA4 (0.40) | GRIA4ALDH1A1 | |
| SCHEMBL9865499 | 0.77 | ALDH1A1 (0.47) | GRIA4ALDH1A1HTTKDM4ENPSR1 | |
| SCHEMBL9865512 | 0.74 | GRIA4 (0.48) | GRIA4GRIA2MAPK1ALDH1A1HTT | |
| SCHEMBL9864823 | 0.74 | ALDH1A1 (0.39) | GRIA4ALDH1A1HTTKDM4ENPSR1 | |
| SCHEMBL9866387 | 0.73 | GRIA4 (0.34) | GRIA4GRIA2CCNCCDK8CDK19 | |
| SCHEMBL9865380 | 0.73 | ALDH1A1 (0.47) | ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL9864453 | 0.67 | GRIA4 (0.45) | GRIA4GRIA2CCNCCDK8CDK19 | |
| SCHEMBL9865433 | 0.67 | GRIA4 (0.56) | GRIA4GRIA2MAPK1ALDH1A1HTT | |
| SCHEMBL3137621 | 0.64 | GRIA4 (0.68) | GRIA4GRIA2CCNCCDK8CDK19 | |
| SCHEMBL5639428 | 0.64 | ALDH1A1 (0.50) | GRIA4GRIA2CCNCCDK8CDK19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4994485-A | Seed and soil fungi, bacteria | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1991-02-19 | — | — | US | disclosed |
| EP-0234622-B1 | NEW THIO COMPOUNDS HAVING FUNGICIDAL ACTIVITY | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1990-06-27 | — | — | EP | disclosed |
| EP-0234622-A1 | New thio compounds having fungicidal activity | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1987-09-02 | — | — | EP | disclosed |