SCHEMBL9865813

SCHEMBL9865813

CCCCOc1cc[c]c(F)c1F

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 4/20 0.41
CYP2C19 P33261 4/20 0.41
CYP2C9 P11712 3/20 0.41
CYP19A1 P11511 2/20 0.36
GLA P06280 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
L3MBTL1 Q9Y468 3/20 0.35
LTA4H P09960 4/20 0.34
CYP2D6 P10635 3/20 0.34
TDP1 Q9NUW8 2/20 0.34
ESR1 P03372 1/20 0.34
MCHR1 Q99705 1/20 0.33
TLR8 Q9NR97 1/20 0.33
NR5A1 Q13285 1/20 0.33
GAA P10253 1/20 0.33
TSHR P16473 1/20 0.33
CYP3A4 P08684 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9866957 0.95 L3MBTL1 (0.38) CYP1A2CYP2C19CYP2C9L3MBTL1LTA4H
SCHEMBL9698544 0.93 MEN1 (0.39) CYP1A2CYP2C19CYP2C9L3MBTL1ESR1
SCHEMBL9699906 0.93 MEN1 (0.39) CYP1A2CYP2C19CYP2C9L3MBTL1ESR1
SCHEMBL9698626 0.93 MEN1 (0.39) CYP1A2CYP2C19CYP2C9L3MBTL1ESR1
SCHEMBL9699822 0.93 MEN1 (0.39) CYP1A2CYP2C19CYP2C9L3MBTL1ESR1
SCHEMBL1005007 0.91 MAPT (0.40) CYP1A2CYP2C19CYP2C9SMN1; SMN2L3MBTL1
SCHEMBL2959622 0.84 CYP1A2 (0.40) CYP1A2CYP2C19CYP2C9CYP19A1GLA
SCHEMBL1003999 0.83 L3MBTL1 (0.38) CYP1A2CYP2C19GLASMN1; SMN2L3MBTL1
SCHEMBL921028 0.79 CYP1A2 (0.49) CYP1A2CYP2C19CYP2C9CYP19A1GLA
SCHEMBL15120786 0.78 CYP1A2 (0.50) CYP1A2CYP2C19CYP2C9CYP19A1GLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114671744-B Green method for synthesizing biaryl structure-containing compound through Suzuki coupling reaction 江苏和成新材料有限公司 2024-04-05 CN disclosed
CN-114671745-B Green method for synthesizing biaryl structure-containing compound through Suzuki coupling reaction 江苏和成新材料有限公司 2024-04-05 CN disclosed
CN-116064046-A Liquid crystal compound, liquid crystal composition thereof and liquid crystal display device 江苏和成显示科技有限公司 2023-05-05 CN disclosed
CN-110117277-A A kind of new structure negative liquid crystal monomer and preparation method 河北迈尔斯通电子材料有限公司 2019-08-13 CN disclosed
CN-107001936-A Liquid crystal compound and liquid crystal composition containing same 株式会社东进世美肯 2017-08-01 CN disclosed
US-5032312-A Liquid crystals HOFFMANN-LA ROCHE INC. (US) 1991-07-16 US disclosed