Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 2/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4927166 | 0.88 | KDM5A (0.50) | KDM5AHDAC1MAPTHTTKDM4E | |
| SCHEMBL3256083 | 0.88 | NPC1 (0.54) | MAPTKDM4EPOLBMEN1KMT2A | |
| SCHEMBL2934675 | 0.87 | CA12 (0.54) | HDAC1MAPTHTTKDM4EGAA | |
| SCHEMBL17486759 | 0.85 | HDAC1 (0.48) | HDAC1HTTKCNMA1KMT2ACYP17A1 | |
| SCHEMBL2890796 | 0.85 | MAPT (0.46) | MAPTKDM4EGAAMEN1KMT2A | |
| SCHEMBL30779358 | 0.85 | MAPT (0.46) | MAPTKDM4EGAAMEN1KMT2A | |
| SCHEMBL2283371 | 0.85 | PPARG (0.51) | HDAC1MAPTKDM4EGAAL3MBTL1 | |
| SCHEMBL23754439 | 0.84 | PPARG (0.52) | HDAC1MAPTHTTKDM4EPOLB | |
| SCHEMBL30955674 | 0.84 | PPARG (0.52) | HDAC1MAPTHTTKDM4EPOLB | |
| SCHEMBL14876843 | 0.84 | AAK1 (0.46) | HDAC1MAPTHTTKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160032047-A1 | Peg-based adhesive phenylic derivatives and methods of synthesis and use | DSM IP ASSETS B.V. (NL) | 2016-02-04 | — | — | US | disclosed |
| EP-2968667-A1 | PEG-BASED ADHESIVE PHENYLIC DERIVATIVES AND METHODS OF SYNTHESIS AND USE | DSM IP Assets B.V. (NL) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014158288-A1 | PEG-BASED ADHESIVE PHENYLIC DERIVATIVES AND METHODS OF SYNTHESIS AND USE | DSM IP ASSETS B.V. (NL) | 2014-10-02 | — | — | WO | disclosed |
| US-5039805-A | Novel benzoic and phenylacetic acid derivatives | HOFFMANN-LA ROCHE INC. (US) | 1991-08-13 | — | — | US | disclosed |