Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 7/20 | 0.41 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TERT | O14746 | 1/20 | 0.39 |
| ▸ | TOP1 | P11387 | 1/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.38 |
| ▸ | PLK1 | P53350 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17486761 | 0.89 | CYP17A1 (0.42) | HDAC1KMT2ALCKCYP17A1NAMPT | |
| SCHEMBL11982645 | 0.86 | HDAC1 (0.46) | HDAC1LCK | |
| SCHEMBL9865843 | 0.85 | KDM5A (0.50) | HDAC1KCNMA1KMT2ACYP17A1HTT | |
| SCHEMBL2934675 | 0.84 | CA12 (0.54) | HDAC1KMT2ALCKHPGDHTT | |
| SCHEMBL31495873 | 0.82 | LCK (0.43) | HDAC1KMT2ALCKCYP17A1NAMPT | |
| SCHEMBL31495872 | 0.82 | LCK (0.43) | HDAC1KMT2ALCKCYP17A1NAMPT | |
| SCHEMBL30871575 | 0.82 | CYP17A1 (0.55) | HDAC1KMT2ALCKCYP17A1RXFP1 | |
| SCHEMBL2031546 | 0.80 | KCNMA1 (0.54) | KCNMA1HPGDHTTSMN1; SMN2 | |
| SCHEMBL14980804 | 0.79 | CYP17A1 (0.43) | HDAC1KCNMA1CYP17A1NAMPTRXFP1 | |
| SCHEMBL31458629 | 0.78 | KCNMA1 (0.54) | KCNMA1KMT2AHPGDTSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160032047-A1 | Peg-based adhesive phenylic derivatives and methods of synthesis and use | DSM IP ASSETS B.V. (NL) | 2016-02-04 | — | — | US | disclosed |