Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.61 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.61 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.61 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | CLK2 | P49760 | 1/20 | 0.50 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TOP2A | P11388 | 7/20 | 0.47 |
| ▸ | TOP2B | Q02880 | 7/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9864929 | 0.91 | KCNH2 (0.54) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL9378400 | 0.86 | KCNH2 (0.56) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL9865679 | 0.84 | ALDH1A1 (0.61) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL9378328 | 0.81 | KCNH2 (0.55) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL9670688 | 0.81 | ALDH1A1 (0.65) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL9865664 | 0.81 | ALDH1A1 (0.60) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL9671157 | 0.81 | ALDH1A1 (0.69) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL9866284 | 0.80 | KDM4E (0.61) | ALDH1A1KDM4EHPGDHSD17B10TOP2A | |
| SCHEMBL9865688 | 0.80 | ALDH1A1 (0.54) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL9866672 | 0.80 | KDM4E (0.61) | ALDH1A1POLBOPRM1KCNH2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4962108-A | A QUIN-4-ONE HAVING THE FOLLOWING RING SUBSTITUENTS; 1-ALKYL OR PHENYL, 3-CARBOXY DERIVATIVE, 6-FLUORO AND 8-BRIDGED N-HETEROCYCLIC RING | WARNER-LAMBERT COMPANY (US) | 1990-10-09 | — | — | US | claimed |
| US-4992546-A | Process for preparing 6,8-diazabicyclo[3.2.2]nonane derivatives | WARNER-LAMBERT COMPANY (US) | 1991-02-12 | — | — | US | disclosed |
| US-4968799-A | Antibacterial agents | WARNER-LAMBERT COMPANY (US) | 1990-11-06 | — | — | US | disclosed |
| US-4962108-A | A QUIN-4-ONE HAVING THE FOLLOWING RING SUBSTITUENTS; 1-ALKYL OR PHENYL, 3-CARBOXY DERIVATIVE, 6-FLUORO AND 8-BRIDGED N-HETEROCYCLIC RING | WARNER-LAMBERT COMPANY (US) | 1990-10-09 | — | — | US | disclosed |
| US-4923879-A | CARBOXYLIC ACID DERIVATIVES WITH BRIDGED SIDECHAINS | WARNER-LAMBERT COMPANY (US) | 1990-05-08 | — | — | US | disclosed |
| EP-0305744-A2 | Quinoline, naphthyridine and benzoxazine-carboxylic acid derivatives and their use as antibacterial agents | WARNER-LAMBERT COMPANY (US) | 1989-03-08 | — | — | EP | disclosed |