Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10445029 | 0.91 | MAPT (0.35) | THRBMAPTKDM4EMEN1CYP1A2 | |
| SCHEMBL9865164 | 0.89 | MAOB (0.37) | MAPTKDM4EALDH1A1GAAMEN1 | |
| SCHEMBL9866296 | 0.88 | MCHR1 (0.37) | THRBMAPTMAPK14KDM4EALDH1A1 | |
| SCHEMBL9602742 | 0.79 | HRH3 (0.45) | MAPTKDM4EALDH1A1GAAMEN1 | |
| SCHEMBL10445204 | 0.78 | HRH3 (0.42) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL9866585 | 0.78 | MCHR1 (0.38) | THRBMAPTKDM4EMEN1CYP1A2 | |
| SCHEMBL9866081 | 0.78 | HRH3 (0.33) | HRH3NR3C1 | |
| SCHEMBL9867229 | 0.78 | TOP1 (0.40) | MAPTKDM4EALDH1A1GAANPC1 | |
| SCHEMBL9866371 | 0.77 | HRH3 (0.41) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL9602962 | 0.77 | HRH3 (0.36) | MAPTKDM4EALDH1A1MEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5045541-A | Immunodeficiency disorders | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1991-09-03 | — | — | US | disclosed |
| EP-0351435-A1 | FUSED PYRIDAZINE COMPOUNDS AND THEIR MEDICINAL USES | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1990-01-24 | — | — | EP | disclosed |