Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | MMP12 | P39900 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.30 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9602962 | 0.87 | HRH3 (0.36) | HRH3CA12CA1CA2CA9 | |
| SCHEMBL9603117 | 0.86 | CDK4 (0.39) | — | |
| SCHEMBL9601577 | 0.84 | MCHR1 (0.37) | HRH3CA12CA1CA2CA9 | |
| SCHEMBL10445204 | 0.80 | HRH3 (0.42) | HRH3 | |
| SCHEMBL9867408 | 0.80 | ALDH1A1 (0.37) | CA12CA1CA2CA9MMP12 | |
| SCHEMBL9866342 | 0.80 | MCHR1 (0.36) | HRH3CA12CA1CA2CA9 | |
| SCHEMBL9866572 | 0.79 | MMP12 (0.40) | HRH3CA12CA1CA2CA9 | |
| SCHEMBL9865465 | 0.78 | MCHR1 (0.38) | HRH3CA12CA1CA2CA9 | |
| SCHEMBL9866045 | 0.78 | THRB (0.34) | HRH3NR3C1 | |
| SCHEMBL9602675 | 0.78 | TOP1 (0.38) | HRH3CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5045541-A | Immunodeficiency disorders | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1991-09-03 | — | — | US | disclosed |
| EP-0351435-A1 | FUSED PYRIDAZINE COMPOUNDS AND THEIR MEDICINAL USES | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1990-01-24 | — | — | EP | disclosed |